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Table 2 Effect of low protein diet with and without supplemental folate on erythrocyte and liver glutathione in rats

From: Preovulatory exposure to a protein-restricted diet disrupts amino acid kinetics and alters mitochondrial structure and function in the rat oocyte and is partially rescued by folic acid

 

Control (n = 8)

LP (n = 8)

LPF (n = 8)

P value

Cysteine

 Plasma Concentration (μmol·L− 1)

167 ± 5.95 a

180 ± 12.8 ab

218 ± 16.8 b

0.0268

Glutathione

 Erythrocyte

  Concentration (mmol·L− 1)

2.97 ± 0.12 a

4.11 ± 0.19 b

4.12 ± 0.35 b

0.003

  ASR (mmol·kg− 1·h− 1)

0.59 ± 0.14

0.91 ± 0.15

0.55 ± 0.13

0.145

 Liver

  Concentration (mmol·L− 1)

4.00 ± 0.29 a

6.02 ± 0.24 b

5.82 ± 0.40 b

0.0003

  ASR (mmol·kg− 1·h− 1)

4.87 ± 1.13

6.67 ± 1.45

4.45 ± 0.78

0.383

  1. Note: Data are mean ± SEM; LP = Low Protein; LPF = Low Protein with supplemental folate ASR = absolute synthesis rate. Means with different superscript letters are significantly different, P < 0.05 (Tukey’s multiple comparison test)
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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