Table 2 Comparison of stimulation and cycle outcomes in the two study groups
Variablesa | Delayed start group (N = 60) | Control group (N = 60) | 95% CI | P value |
|---|---|---|---|---|
Total rFSH dose (IU) | 2210.0 ± 559.4 | 2897.0 ± 952.0 | (− 969.8–405.1) | < 0.001 |
Total hMG dose (IU) | 1122.5 ± 272 | 1487 ± 486 | (− 507.4–222.5) | < 0.001 |
Duration of stimulation (day) | 9.3 ± 1.7 | 12.3 ± 3.6 | (− 3.9–1.8) | < 0.001 |
No. of retrieved oocytes | 3.2 ± 2.7 | 2.0 ± 2.1 | (0.22–2.0) | 0.01* |
No. of metaphase II oocytes | 2.5 ± 2.2 | 1.8 ± 1.9 | (−0.06–1.4) | 0.07 |
The cases with no oocyte result, n (%) | 6 (10) | 2 (3.4) | – | 0.1 |
Cancellation rate (no response), n (%) | 0 (0) | 18 (30.0) | – | < 0.001 |
Fertilization rate | 73.4 ± 36.3 | 42.6 ± 36.7 | (15.4–46.0) | < 0.001* |
No. of obtained embryos | 2.3 ± 1.6 | 1.7 ± 0.8 | (−0.07–1.2) | 0.02* |
No. of top quality embryo | 1.5 ± 1.3 | 1.0 ± 0.7 | (−0.06–1.0) | 0.02* |
The cases with no embryo result, n (%) | 8 (13.3) | 12 (20.0) | – | 0.3 |
No. of embryos transferred | 1.8 ± 0.9 | 1.7 ± 0.8 | (−0.04–0.5) | 0.7 |
Endometrial thickness at trigger (mm) | 9.3 ± 1.2 | 8.7 ± 0.9 | (0.12–0.96) | 0.01* |
Implantation rate | 41.6 (33.3–50) | 50 (50–50) | – | 0.5 |
Clinical pregnancy/ ET (%) | 4/46 (8.7) | 2/28 (7.1) | – | 0.8 |
Miscarriage rate/ET (%) | 0 (0) | 1 (3.5) | – | 0.1 |