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Table 1 Demographic and clinical characteristics of study participants in two groups

From: Does the “delayed start” protocol with gonadotropin-releasing hormone antagonist improve the pregnancy outcome in Bologna poor responders? a randomized clinical trial

Variables Control group (N = 60) Delayed start group (N = 60) P value
Female age (yr.) 39.5 ± 4.8 40.5 ± 4.48 0.2
Body mass index (kg/m2) 26.1 ± 3.2 26.8 ± 3.0 0.2
Duration of Infertility (yr.) 9.2 ± 6.7 7.9 ± 5.2 0.2
No. of couple with primary infertility n (%) 44 (73.3) 42 (70.0) 0.8
Early follicular phase FSH (IU/L) 8.7 ± 3.3 8.0 ± 2.8 0.3
Early follicular phase LH (IU/L) 5.5 ± 4.2 6.5 ± 4.5 0.1
Early follicular phase AMH (ng/mL) 0.53 ± 0.31 0.55 ± 0.30 0.8
Serum level of TSH (IU/mL) 1.7 ± 0.8 1.9 ± 1.1 0.2
Serum level of Prolactin (ng/mL) 17.8 ± 10.0 17.8 ± 8.7 0.6
Antral follicle count 5.0 ± 1.8 4.7 ± 1.2 0.3
No. of previous failed cycles 1.5 ± 1.2 1.3 ± 1.0 0.1
Subgroups of POR according to Bologna criteria n, (%)    0.2
Subgroup A 0 0  
Subgroup B 18 (30) 19 (31.7)  
Subgroup C 18 (30) 10 (16.6)  
Subgroup D 24 (40) 31 (51.7)  
  1. Descriptive data were presented as Mean ± SD. P-value≤0.05 was considered statistically significant
  2. No number, FSH Follicle stimulating hormone, LH = Luteinizing hormone, TSH = Thyroid stimulating hormone, AMH Anti-müllerian hormone, E2 = estradiol, P = Progesterone
  3. Subgroup A: (female age ≥ 40, and a previous poor response (cycle cancelled or ≤ 3 oocytes)
  4. Subgroup B: female age ≥ 40 with an abnormal antral follicle count (AFC) < 7 and AMH level
  5. Subgroup C: abnormal AFC < 7 and AMH < 1.1 ng/ ml with a previous poor response
  6. Subgroup D: female age ≥ 40 with an AFC < 7 and AMH < 1.1 ng/ ml and previous poor response