Table 2 Results of meta-analyses and test of publication bias on oocytes
Outcomes | Study type | No. of studies | Events/Total | RR, 95%CI, P | Test of Heterogeneity | Tests of Publication Bias | |||
|---|---|---|---|---|---|---|---|---|---|
Closed | Open | Random | I2 (%) | P | Begg’s P | Egger’s P | |||
Cryosurvival rate | Prospective | 4 | 830/986 | 967/1062 | 0.91, [0.80, 1.03], 0.14 | 91% | 0.00 | 1.000 | 0.921 |
Retrospective | 1 | 222/268 | 151/261 | 1.43, [1.27, 1.61], < 0.01 | NA | NA | NA | NA | |
Fertilization rate | Prospective | 2 | 585/733 | 594/784 | 1.02, [0.83, 1.24], 0.88 | 92% | 0.00 | 1.000 | NA |
Retrospective | 1 | 116/159 | 87/151 | 1.27, [1.07, 1.50], < 0.01 | NA | NA | NA | NA | |
Good quality embryo rate | Prospective | 2 | 229/561 | 240/566 | 0.97, [0.84, 1.11], 0.62 | 0% | 0.96 | 1.000 | NA |
Retrospective | 1 | 62/112 | 30/87 | 1.61, [1.15, 2.24], < 0.01 | NA | NA | NA | NA | |
Positive βHCG rate | Prospective | 2 | 45/109 | 47/125 | 1.09, [0.75, 1.59], 0.64 | 22% | 0.26 | 1.000 | NA |
Miscarriage rate | Prospective | 2 | 4/38 | 8/39 | 0.59, [0.20, 1.79], 0.35 | 0% | 0.84 | 1.000 | NA |
Ongoing pregnancy rate | Prospective | 2 | 38/125 | 27/109 | 1.24, [0.81, 1.89], 0.32 | 0% | 0.45 | 1.000 | NA |
Clinical pregnancy rate | Prospective | 1 | 27/75 | 21/75 | 1.29, [0.80, 2.06], 0.30 | NA | NA | NA | NA |
Retrospective | 1 | 14/53 | 4/51 | 3.37, [1.19, 9.55], 0.02 | NA | NA | NA | NA | |
Live birth rate | Prospective | 1 | 27/75 | 18/75 | 1.50, [0.91, 2.48], 0.11 | NA | NA | NA | NA |
Retrospective | 1 | 11/53 | 3/51 | 3.53, [1.04, 11.92], 0.04 | NA | NA | NA | NA | |