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Table 2 Results of overall and subgroup analyses for ADIPOQ gene polymorphisms and PCOS

From: Effects of ADIPOQ polymorphisms on PCOS risk: a meta-analysis

Population Sample size Dominant comparison Recessive comparison Additive comparison Allele comparison
P value OR (95%CI) I2 statistic P value OR (95%CI) I2 statistic P value OR (95%CI) I2 statistic P value OR (95%CI) I2 statistic
rs1501299 G/T   GG vs. GT + TT TT vs. GG + GT GT vs. GG + TT G vs. T
Overall 2602/3773 0.10 1.17 (0.97–1.42) 52% 0.02 0.77 (0.62–0.95) 46% 0.52 0.94 (0.76–1.15) 58% 0.001 1.15 (1.06–1.26) 43%
Caucasian 685/545 0.007 1.40 (1.09–1.79) 42% 0.79 0.94 (0.62–1.45) 0% 0.01 0.73 (0.58–0.93) 48% 0.03 1.22 (1.02–1.46) 22%
East Asian 509/568 0.006 1.41 (1.10–1.81) 37% 0.0003 0.48 (0.32–0.71) 0% 0.76 0.96 (0.75–1.23) 17% 0.0001 1.44 (1.20–1.73) 2%
West Asian 803/688 0.19 0.87 (0.71–1.07) 4% 0.88 0.95 (0.47–1.89) 70% 0.30 1.19 (0.85–1.68) 62% 0.52 0.95 (0.81–1.11) 31%
rs2241766 T/G   TT vs. TG + GG GG vs. TT + TG TG vs. TT + GG T vs. G
Overall 2358/4034 0.63 1.03 (0.91–1.18) 46% 0.54 1.10 (0.81–1.50) 41% 0.44 0.95 (0.83–1.09) 44% 1.00 1.00 (0.84–1.19) 54%
Caucasian 966/1280 0.32 0.89 (0.70–1.12) 22% 0.04 1.93 (1.05–3.56) 26% 0.84 1.03 (0.80–1.31) 6% 0.11 0.84 (0.68–1.04) 46%
East Asian 509/568 0.74 0.93 (0.62–1.40) 61% 0.86 1.10 (0.40–3.02) 59% 0.54 1.17 (0.71–1.93) 73% 0.95 0.99 (0.73–1.35) 58%
West Asian 803/686 0.31 1.22 (0.83–1.80) 65% 0.56 0.85 (0.49–1.47) 8% 0.31 0.83 (0.59–1.18) 53% 0.32 1.19 (0.84–1.69) 67%
  1. OR Odds ratio, CI Confidence interval, NA Not available. PCOS Polycystic ovary syndrome
  2. The values in bold represent there is statistically significant differences between cases and controls