Table 1 Radiation doses and risk of gonadal failure (High risk: > 80% sterilized; Mild risk: 20–80% sterilized; Low risk: < 20% sterilized)
Radiation Doses | Risk of Ovarian Failure | ||
|---|---|---|---|
Prepubertal girls | 15–40 years | > 40 years | |
Pelvic/abdominal irradiation | |||
< 6Gy | Mild risk | No adverse effects | No adverse effects |
15 Gy | High risk | Low risk | Mild risk |
25–50 Gy | High risk | Mild risk | High risk |
50–80 Gy | High risk | Mild risk | High risk |
> 80 Gy | High risk | High risk | High risk |
Cranio-spinal irradiation > 25 Gy | Mild risk | Mild risk | Mild risk |
Total body irradiation | High risk | High risk | High risk |