Fig. 5
From: Protective effects of mangafodipir against chemotherapy-induced ovarian damage in mice
Expressions of 4-HNE and Ki67 in primordial follicles. a Representative images of immunohistochemistry for 4-HNE in primordial follicles of murine ovaries treated with 7.5 (CIS7.5) or 20 (CIS20) mg/kg cisplatin, 7.5 (PTV7.5) or 20 (PTX20) mg/kg paclitaxel, with or without mangafodipir (+/− Mangafodipir, respectively). Bar, 100 μm. b Representative images of immunohistochemistry for Ki67 in primordial follicles of murine ovaries treated with 20 (CIS20) mg/kg cisplatin, or 7.5 (PTX7.5) or 20 (PTX20) mg/kg paclitaxel, with or without mangafodipir (+/− Mangafodipir, respectively). Bar, 100 μm. c The percentage of Ki67-positive primordial follicles. Mean ± SEM, *, p < 0.05