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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: Protective effects of mangafodipir against chemotherapy-induced ovarian damage in mice

Fig. 2

Effects of mangafodipir on the number of follicles at each development stage and on the rate of healthy follicles after anticancer treatment. a Representative images of ovaries on day 7 after the administration of 7.5 or 20 mg/kg cisplatin (CIS), or 7.5 or 20 mg/kg paclitaxel (PTX), with or without mangafodipir (+/− Mangafodipir, respectively). Bar, 100 μm. b The total number of follicles at each developing stage (primordial, primary, secondary, antral) after the administration of 7.5 (CIS7.5) or 20 (CIS20) mg/kg cisplatin, 7.5 (PTX7.5) or 20 (PTX20) mg/kg paclitaxel, with or without mangafodipir (+/− Mangafodipir, respectively). Mean ± SD, *, p < 0.01. c The rates of healthy follicles after the administration of cisplatin and paclitaxel, with or without mangafodipir. Mean ± SD, *, p < 0.05

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