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Table 1 The Characteristics of Selected Studies

From: Meta-analysis of ART outcomes in women with different preconception TSH levels

Author Year N Country Study design Assays
used
TSH
Cut-off
ART
details
Outcomes
Coelho 2016 650 Brazil retrospective a third-generation assay 2.5:4.0 IVF/ICSI PR; CPR; LBR; MR
Aghahosseini 2013 816 Iran retrospective NS 2.5 IVF CPR
Mintziori 2014 158 Greece retrospective ELISA 2.5 IVF PR; CPR; LBR; MR
Unuane 2017 3143 Belgium retrospective NS 2.5 IUI PR; LBR; MR
Michalakis 2011 1216 USA retrospective NS 2.5;4.0 NS PR; CPR; LBR; MR
Muller 1999 141 Netherlands prospective an immunoluminometric assay 4.5 IVF PR; LBR; MR
Chai 2014 505 China retrospective Access HYPERsensitive hTSH
Reagent Pack and Access Free
T4 Reagent Pack
2.5;4.5 IVF/
ICSI
CPR; LBR; MR
Baker 2006 146 USA retrospective chemiluminometric technology 2.5 IVF LBR
Karmon 2014 1477 USA prospective third-generation assays 2.5 IUI CPR; LBR
Weghofer 2015 98 USA retrospective Electrochemiluminescence
immunoassay
2.5 IVF CPR; LBR
Seungdamrong 2017 1306 USA prospective Immulite 2000 system 2.5 IUI PR; CPR; LBR; MR
Wu 2017 138 China prospective NS 2.5; 5 IVF/
ICSI
PR; CPR; LBR; MR
Ba 2013 413 China prospective NS 4.2 IVF/
ICSI
PR; CPR; LBR; MR
Zhang 2012 1832 China retrospective NS 3.9 IVF/
ICSI
PR; CPR; LBR; MR
Zeng 2014 375 China prospective Chemiluminescent
immunoassay
2.5;3.5 IVF/
ICSI
CPR; LBR; MR
Gingold 2016 1201 USA retrospective NS 2.5;5.0 IVF PR; CPR; LBR
Reh 2010 1055 USA retrospective NS 2.5;4.5 IVF CPR; LBR; MR
Cai 2017 176 China prospective electro- chemiluminescence immunoassays 2.5 IVF CPR; LBR; MR
  1. IVF In vitro fertilization, ICSI intracytoplasmatic sperm injection, IUI intra-uterine insemination, ART assisted reproduction technology, TSH thyroid stimulating hormone, CPR clinical pregnancy rate, MR miscarriage rate, LBR live birth rate, PR pregnancy rate, ELISA enzyme-linked immunosorbent assay