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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: Spatio-temporal expression profile of matrix metalloproteinase (Mmp) modulators Reck and Sparc during the rat ovarian dynamics

Fig. 2

mRNA expression profile of matrix metalloproteinases (Mmps) during ovary dynamics across hormone-induced estrous cycle in rats. (a) Mmp2, (b) Mmp9, (c) Mmp13 and (d) Mmp14. Expression levels were normalized to the average expression of control animals treated with saline solution. The statistical significances were relative to control group. * Mmp2 expression level was lower in the corpus luteum (G7) (p < 0.05). ** Mmp2 levels were significantly higher at the ovulation-luteogenesis transition phase (G5) and lower at late stages of the CL maintenance and luteolysis G8-G9 (p < 0.01). *** Mmp2 levels were significantly higher in early folliculogenesis ovaries (G2) than in ovaries from the control group; Mmp9 levels were higher at ovulation-luteinization Transition (G5) and luteinization (G6); Mmp13 were levels higher at late stages of the CL maintenance and luteolysis (G8-G9) (p < 0.001)

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