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Table 4 Total gonadotropin dose administered, response to COH in terms of serum estradiol levels and number of oocytes recovered, and stimulation days with gonadotropins until the day of hCG administration in oocyte donors and infertile women undergoing ART, according to the -29G > A single nucleotide polymorphism of the FSHR. Numbers are mean ± S.D., unless indicated

From: Frequency of the T307A, N680S, and -29G>A single-nucleotide polymorphisms in the follicle-stimulating hormone receptor in Mexican subjects of Hispanic ancestry

 

Parameter

GG

GA

AA

Oocyte donors (n = 69)

 

Number

16

37

16

 

Age*

24 (21–28)

24 (19–29)

23.5 (18–27)

 

Total FSH (IU)

1874.3 ± 629.9

1681.3 ± 698.2

1921.6 ± 603.9**

 

Total LH (IU)

1500.0 ± 698.7

1710.4 ± 905.8

2217.8 ± 797.1

 

Estradiol (pg(ml)

2471.3 ± 1320.2

2445.6 ± 1069.2

2559.1 ± 1156.6

 

Oocyte number

12.5 ± 4.5

13.9 ± 5.5

13.3 ± 4.5

 

Stimulation days

10.3 ± 1.4

9.9 ± 1.7

10.5 ± 1.5

Infertile women (n = 125)

 

Number

40

59

26

 

Age*

35 (27–42)

36 (22–43)

35.5 (26–39)

 

Total FSH (IU)

2367.8 ± 655.95

2178.7 ± 599.05

2395.6 ± 696.4**

 

Total LH (IU)

802.08 ± 637.9

708.1 ± 431.5

831.3 ± 478.9

 

Estradiol (pg(ml)

2088.6 ± 1134.9

2116.93 ± 1039.6

1917.8 ± 966.9

 

Oocyte number

8.8 ± 5.8

8.9 ± 5.4

8.7 ± 5.2

 

Stimulation days

10.02 ± 1.7

10.0 ± 1.9

10.5 ± 1.5

  1. *Median and range
  2. **None of the parameters analyzed were statistically different among genotypes (p ≥ 0.711 and p ≥ 0.964 for parameters in the donor and infertile group, respectively)