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Table 3 Total gonadotropin dose administered, response to COH in terms of serum estradiol levels and number of oocytes recovered, and stimulation days with gonadotropins until the day of hCG administration in oocyte donors and infertile women undergoing ART, according to the c.2039A > G (N680S) single nucleotide polymorphism at the FSHR. Numbers are means ± S.D., unless indicated

From: Frequency of the T307A, N680S, and -29G>A single-nucleotide polymorphisms in the follicle-stimulating hormone receptor in Mexican subjects of Hispanic ancestry

  Parameter NN NS SS
Oocyte donors (n = 69)
  Number 32 32 5
  Age 23.5* (18–29) 24 (20–29) 23 (21–25)
  Total FSH (IU) 1673.3 ± 658.2 1888.7 ± 702.4 1791.7 ± 286.7
  Total LH (IU) 1887.4 ± 917.4 1796.7 ± 826.4 1275.0 ± 742.5
  Estradiol (pg(ml) 2433.6 ± 1094.9 2607.6 ± 1315.9 2431.2 ± 501.8
  Oocyte number 13.7 ± 5.1 13.9 ± 5.14 8.8 ± 1.3**
  Stimulation days 9.9 ± 1.6 10.3 ± 1.6 10.6 ± 1.1
Infertile women (n = 125)
  Number 54 57 14
  Age 35.5* (22–41) 36 (27–43) 34 (25–42)
  Total FSH (IU) 2329.7 ± 682.3 2261.2 ± 644.7 2203.4 ± 463.1
  Total LH (IU) 857.8 ± 639.9 700.7 ± 394.7 664.2 ± 350.3
  Estradiol (pg(ml) 2166.8 ± 1104.1 1977.6 ± 1028.0 2041.1 ± 970.6
  Oocyte number 9.2 ± 4.8 8.2 ± 5.7 9.8 ± 6.8
  Stimulation days 10.3 ± 1.4 10.2 ± 2.0 9.2 ± 1.8
  1. *Median and range
  2. **P = 0.005 vs NN and NS genotypes; the remaining parameters in the donors and all parameters in the infertile group did not differ significantly among genotypes (P ≥ 0.122 and P ≥ 0.135, for parameters in donors and infertile women, respectively)