Table 3 Total gonadotropin dose administered, response to COH in terms of serum estradiol levels and number of oocytes recovered, and stimulation days with gonadotropins until the day of hCG administration in oocyte donors and infertile women undergoing ART, according to the c.2039A > G (N680S) single nucleotide polymorphism at the FSHR. Numbers are means ± S.D., unless indicated
Parameter | NN | NS | SS | |
|---|---|---|---|---|
Oocyte donors (n = 69) | ||||
Number | 32 | 32 | 5 | |
Age | 23.5* (18–29) | 24 (20–29) | 23 (21–25) | |
Total FSH (IU) | 1673.3 ± 658.2 | 1888.7 ± 702.4 | 1791.7 ± 286.7 | |
Total LH (IU) | 1887.4 ± 917.4 | 1796.7 ± 826.4 | 1275.0 ± 742.5 | |
Estradiol (pg(ml) | 2433.6 ± 1094.9 | 2607.6 ± 1315.9 | 2431.2 ± 501.8 | |
Oocyte number | 13.7 ± 5.1 | 13.9 ± 5.14 | 8.8 ± 1.3** | |
Stimulation days | 9.9 ± 1.6 | 10.3 ± 1.6 | 10.6 ± 1.1 | |
Infertile women (n = 125) | ||||
Number | 54 | 57 | 14 | |
Age | 35.5* (22–41) | 36 (27–43) | 34 (25–42) | |
Total FSH (IU) | 2329.7 ± 682.3 | 2261.2 ± 644.7 | 2203.4 ± 463.1 | |
Total LH (IU) | 857.8 ± 639.9 | 700.7 ± 394.7 | 664.2 ± 350.3 | |
Estradiol (pg(ml) | 2166.8 ± 1104.1 | 1977.6 ± 1028.0 | 2041.1 ± 970.6 | |
Oocyte number | 9.2 ± 4.8 | 8.2 ± 5.7 | 9.8 ± 6.8 | |
Stimulation days | 10.3 ± 1.4 | 10.2 ± 2.0 | 9.2 ± 1.8 | |