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Table 1 Allele and genotype frequencies for the single nucleotide polimorphism (SNP) c.919A > G and c.2039A > G of the FSHR in the population of normal oocyte donors and infertile Mexican mestizo women

From: Frequency of the T307A, N680S, and -29G>A single-nucleotide polymorphisms in the follicle-stimulating hormone receptor in Mexican subjects of Hispanic ancestry

Group SNP Allele frequency % Genotype frequency %
Donors (n = 80) c.919A > G (p.T307A) A (T) 68.1& AA (TT) 45.0*
  G (A) 31.8 AG (TA) 46.2
   GG (AA) 8.7
c.2039A > G (p.N680S) A (N) 66.8&& AA (NN) 42.5**
  G (S) 33.1 AG (NS) 48.7
   GG (SS) 8.7
Infertile women (n = 144) c.919A > G (p.T307A) A (T) 69.4 AA (TT) 47.9
  G (A) 30.5 AG (TA) 43.0
   GG (AA) 9.0
c.2039A > G (p.N680S) A (N) 65.6 AA (NN) 41.6
  G (S) 34.3 AG (NS) 48.0
   GG (SS) 10.4
TOTAL (n = 224) c.919A > G (p.T307A) A (T) 68.9 AA (TT) 46.8
  G (A)31.0 AG (TA) 44.2
   GG (AA) 8.9
c.2039A > G (p.N680S) A (N) 66.0 AA (NN) 41.9
  G (S) 34.0 AG (NS) 48.2
   GG (SS) 9.8
  1. &P = 0.930 and &&P = 0.987 vs infertile women for the A and G alleles at positions c.919 and c.2039, respectively
  2. *P = 0.897 and **P = 0.922 vs infertile women for the AA, AG, and GG genotypes at positions c.919 and c.2039, respectively