Table 3 Glycemic control, markers of cardio-metabolic risk and oxidative stress at baseline and after the 8-week intervention in infertile polycystic ovary syndrome women candidate for in vitro fertilization that received either vitamin D supplements or placebo
|  | Placebo group (n = 20) | Vitamin D group (n = 20) | Pa | ||||
|---|---|---|---|---|---|---|---|
Baseline | End-of-trial | Change | Baseline | End-of-trial | Change | ||
Vitamin D (ng/mL) | 11.0 ± 2.4 | 10.9 ± 2.1 | -0.1 ± 0.6 | 10.5 ± 2.5 | 21.7 ± 5.9 | 11.2 ± 5.0 | < 0.001 |
AMH (ng/mL) | 8.7 ± 2.7 | 8.6 ± 2.5 | -0.1 ± 0.5 | 7.7 ± 3.4 | 7.0 ± 3.1 | −0.7 ± 1.2 | 0.02 |
FPG (mg/dL) | 92.9 ± 5.5 | 93.5 ± 5.6 | 0.5 ± 3.0 | 90.3 ± 10.5 | 89.4 ± 10.6 | −0.9 ± 7.4 | 0.42 |
Insulin (μIU/mL) | 11.4 ± 1.9 | 11.1 ± 2.0 | −0.3 ± 0.9 | 11.2 ± 2.2 | 9.8 ± 2.7 | −1.4 ± 1.6 | 0.007 |
HOMA-IR | 2.6 ± 0.5 | 2.5 ± 0.4 | −0.1 ± 0.2 | 2.5 ± 0.7 | 2.2 ± 0.7 | −0.3 ± 0.3 | 0.008 |
QUICKI | 0.33 ± 0.008 | 0.33 ± 0.009 | 0.001 ± 0.004 | 0.33 ± 0.01 | 0.34 ± 0.02 | 0.009 ± 0.01 | 0.04 |
Triglycerides (mg/dL) | 111.5 ± 35.5 | 117.4 ± 34.8 | 5.9 ± 13.2 | 105.3 ± 33.5 | 107.5 ± 38.1 | 2.1 ± 17.4 | 0.44 |
VLDL-cholesterol (mg/dL) | 22.3 ± 7.1 | 23.5 ± 6.9 | 1.2 ± 2.6 | 21.1 ± 6.7 | 21.5 ± 7.6 | 0.4 ± 3.5 | 0.44 |
Total cholesterol (mg/dL) | 197.1 ± 36.3 | 200.0 ± 36.5 | 2.9 ± 10.9 | 203.6 ± 26.6 | 198.5 ± 24.7 | −5.1 ± 12.6 | 0.03 |
LDL-cholesterol (mg/dL) | 124.9 ± 35.9 | 127.4 ± 35.3 | 2.5 ± 10.6 | 133.1 ± 21.1 | 128.7 ± 20.8 | −4.5 ± 10.3 | 0.04 |
HDL-cholesterol (mg/dL) | 49.9 ± 7.5 | 49.1 ± 8.2 | −0.8 ± 3.9 | 49.4 ± 5.7 | 48.4 ± 5.4 | −1.0 ± 2.8 | 0.81 |