Table 2 Cycle characteristics and pregnancy outcome of poor ovarian responders with or without DHEA
Parameters | POR (n = 84) | POR with DHEA (n = 67) | p value |
|---|---|---|---|
Stimulation duration (days) | 10.1 ± 2.2 | 10.5 ± 1.9 | 0.310 |
Gonadotropin dosage (IU) | 2884.4 ± 872.5 | 2975.4 ± 649.4 | 0.126 |
No. of oocytes retrieved (n) | 2.0 ± 1.5 | 3.3 ± 2.5 | < 0.001 |
Oocytes retrieved > 3, % (n) | 14.3 (12/84) | 34.3 (23/67) | 0.004 |
No. of metaphase II oocytes (n) | 1.0 ± 1.1 | 1.9 ± 1.5 | < 0.001 |
Maturation rate (%) | 35.5 ± 36.2 | 56.2 ± 33.9 | < 0.001 |
No. of fertilized oocytes (n) | 1.4 ± 1.2 | 2.3 ± 1.7 | < 0.001 |
Fertilization rate (%) | 58.0 ± 42.5 | 67.9 ± 32.7 | 0.108 |
No. of Day 3 embryos (n) | 1.3 ± 1.2 | 2.1 ± 1.6 | 0.001 |
No. of top-quality Day 3 embryos (n) | 0.4 ± 0.8 | 1.0 ± 1.1 | 0.001 |
Clinical pregnancy rate, % (n) | 7.1 (6/84) | 23.9 (16/67) | 0.004 |
Ongoing pregnancy rate, % (n) | 6.0 (5/84) | 17.9 (12/67) | 0.021 |
Live birth rate, % (n) | 6.0 (5/84) | 16.4 (11/67) | 0.038 |
Cancellation rate, % (n) | 16.7 (14/84) | 10.4 (7/67) | 0.273 |