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Table 1 Number of ovulating rats (numbers of ovulating animals/the numbers of used animals) and mean ± S.E.M. number of ova shed by rats injected with vehicle (Vh) or estradiol valerate (EV) at day 14 of life, and treated with GTD from 7 to 27 days of age (Model 1), or 14 to 34-day of age (Model 2) or at 70 to 90-day of age (Model 3). Rats were sacrificed in the adult stage at days 90–94 of life, on the day of vaginal oestrus

From: Pharmacological sympathetic denervation prevents the development of polycystic ovarian syndrome in rats injected with estradiol valerate

Groups Number of ovulating rats Total number of ova shed
Vh EV Vh EV
Without denervation 10/10 0/10a 14.4 ± 0.7 0c
GTD (days 7–27) 9/10 8/11b 13.0 ± 1.3 11.2 ± 0.7 d
GTD (days 14–34) 11/14 9/10 b 13.2 0.7 10.6 ± 1.4 d
GTD (days 70–90) 10/10 7/12b 10.3 ± 0.8 12.2 ± 0.8d
  1. Number of ovulanting rats a p < 0.05 vs. group treated with Vh; b p < 0.05 vs. group treated with EV (Fisher’s exact probability test); total number of ova shed c p < 0.05 vs. group treated with Vh; d p < 0.05 vs. group treated with EV (Kruskal Wallis test, followed by Mann-Whitney U-test)
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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