Table 8 Associations between week 15 TG (44:1) peak intensities and biomarkers derived from the week 28 OGTT
Biomarker | Discovery Cohort | Validation Cohort | Meta-Analysis | |||||
|---|---|---|---|---|---|---|---|---|
R | p-value | n | R | p-value | n | R | p-value | |
Pre-pregnancy BMI | −0.10 | 0.21 | 170 | −0.06 | 0.31 | 356 | −0.07 (− 0.16, 0.01) | 0.05 |
Fasting glucose concentration | 0.04 | 0.54 | 195 | 0.11 | 0.02 | 478 | 0.09 (0.01, 0.16) | 9.9 × 10−3 |
Glucose concentration 60 min. post 75 g load | 0.16 | 0.03 | 195 | 0.05 | 0.26 | 478 | 0.09 (−0.01, 0.19) | 0.04 |
Fasting insulin concentration | 0.03 | 0.65 | 189 | 0.10 | 0.03 | 476 | 0.08 (0, 0.16) | 0.02 |
HOMA IR | 0.03 | 0.65 | 189 | 0.12 | 8.8 × 10−3 | 475 | 0.09 (0.01, 0.17) | 0.01 |
HOMA B | 0.03 | 0.72 | 189 | 0.05 | 0.26 | 475 | 0.04 (−0.03, 0.12) | 0.13 |