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Table 6 Associations between maternal untransmitted alleles and candidate lipid species’ peak intensity

From: Associations between the maternal circulating lipid profile in pregnancy and fetal imprinted gene alleles: a cohort study

SNP Gene Lipid Discovery Cohort Validation Cohort Meta-Analysis
R p-value n R p-value n R p-value
rs10839220 KRTAP5–6 TG(44:1) 0.113 0.16 154 0.067 0.38 179 0.09 (−0.02, 0.19) 0.05
rs10839220 KRTAP5–6 LysoPCP(18:0) 0.095 0.24 154 0.114 0.10 213 0.11 (0, 0.21) 0.02
rs10839220 KRTAP5–6 PE(34:0) 0.068 0.54 154 0.042 0.40 213 0.05 (−0.05, 0.15) 0.16
rs10839220 KRTAP5–6 DG(36:3) 0.122 0.13 154 0 0.98 190 0.06 (−0.06, 0.17) 0.18
rs4752779 FAM99B TG(44:1) 0.020 0.81 161 0.054 0.47 185 0.04 (−0.07, 0.14) 0.24
rs7131362 FAM99A TG(44:1) 0.119 0.14 153 0.050 0.51 175 0.08 (−0.03, 0.19) 0.07
rs7131362 FAM99A TG(48:0) 0.080 0.43 153 0.065 0.26 198 0.07 (−0.03, 0.18) 0.09
rs17073273 PLAGL1 TG(44:1) 0.131 0.09 170 0.024 0.74 201 0.07 (−0.03, 0.18) 0.09
rs17073273 PLAGL1 TG(55:9) 0 0.98 170 0.123 0.06 228 0.07 (−0.05, 0.19) 0.13
rs17073273 PLAGL1 TG(48:0) 0.094 0.22 170 0.067 0.31 228 0.08 (−0.02, 0.18) 0.06
rs2268445 PLAGL1 TG(44:1) 0.092 0.23 172 0.022 0.76 201 0.05 (−0.05, 0.16) 0.15
  1. Only those lipid species that tagged components with significant fitted models in Metaboanalyst using maternally-transmitted fetal variants are shown