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Table 3 Input data to calculate costs

From: Probabilistic cost-effectiveness analysis of controlled ovarian stimulation with recombinant FSH plus recombinant LH vs. human menopausal gonadotropin for women undergoing IVF

Medications

Dose (IU)

Formulation (IU)

Ex-factory price

Source

r-FSH + r-LH

2453.46

150

€ 72.55

[27]

HP-hMG

2801.49

75

€ 16.10

[27]

Pre-treatment tests

Frequency

Unit cost

Source

 Hysterosalpingography

1

€ 116.10

[14], expert opinion

 Transvaginal ultrasound

1

€ 45.90

[14], expert opinion

 Gynaecological consultation

1

€ 21.30

[14], expert opinion

 Serum oestradiol (E2)

1

€ 14.30

[14], expert opinion

 Follicle-stimulating Hormone (FSH)

1

€ 11.90

[14], expert opinion

 Fertility test of the seminal fluid

1

€ 7.90

[14], expert opinion

 Luteinising Hormone (LH)

1

€ 12.90

[14], expert opinion

 Prolactin (PLR)

1

€ 12.70

[14], expert opinion

 Thyroid-stimulating Hormone (TSH)

1

€ 12.40

[14], expert opinion

 Free thyroxine (FT4)

1

€ 12.60

[14], expert opinion

 Free triiodothyronine (FT3)

1

€ 12.70

[14], expert opinion

 Blood samples drawing

1

€ 2.70

[14], expert opinion

Tests during each IVF cycle

Frequency

Unit cost

Source

 Transvaginal ultrasound

3

€ 45.90

[14], expert opinion

 Gynaecological consultation

3

€ 21.30

[14], expert opinion

 Serum oestradiol (E2)

3

€ 14.30

[14], expert opinion

 Blood samples

3

€ 2.70

[14], expert opinion

  1. IU International Unit