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Table 2 Transition probabilities used in the model

From: Probabilistic cost-effectiveness analysis of controlled ovarian stimulation with recombinant FSH plus recombinant LH vs. human menopausal gonadotropin for women undergoing IVF

 

r-FSH + r-LH

HP-hMG

p-value for comparison

Source

≥ 5 Oocytes

 Positive hCG test (MIN - MAX)

0.34 (0.31–0.37)

0.23 (0.21–0.25)

0.007

Analyses from [17]

 Negative hCG test (MIN - MAX)

0.66 (0.60–0.73)

0.77 (0.69–0.84)

 Clinical pregnancy (MIN - MAX)

0.84 (0.76–0.92)

0.82 (0.74–0.90)

0.790

 Miscarriage (MIN - MAX)

0.16 (0.15–0.18)

0,18 (0.16–0.19)

5–9 oocytes

 Positive hCG test (MIN - MAX)

0.28 (0.26–0.31)

0.22 (0.20–0.24)

0.158

Analyses from [17]

 Negative hCG test (MIN - MAX)

0.72 (0.65–0.79)

0.78 (0.70–0.86)

 Clinical pregnancy (MIN - MAX)

0.82 (0.74–0.90)

0.79 (0.71–0.86)

0.646

 Miscarriage (MIN - MAX)

0.18 (0.16–0.19)

0.21 (0.19–0.24)

10–15 oocytes

 Positive hCG test (MIN - MAX)

0.43 (0.39–0.48)

0.24 (0.22–0.27)

0.025

Analyses from [17]

 Negative hCG test (MIN - MAX)

0.57 (0.51–0.62)

0.76 (0.68–0.83)

 Clinical pregnancy (MIN - MAX)

0.88 (0.80–0.97)

0.87 (0.78–0.95)

1.000

 Miscarriage (MIN - MAX)

0.12 (0.10–0.13)

0.13 (0.12–0.15)

> 15 oocytes

 Positive hCG test (MIN - MAX)

0.56 (0.50–0.61)

0.33 (0.30–0.37)

0.202

Analyses from [17]

 Negative hCG test (MIN - MAX)

0.44 (0.40–0.49)

0.67 (0.60–0.73)

 Clinical pregnancy (MIN - MAX)

0.80 (0.72–0.88)

1.00 (0.90–1.00)

0.524

 Miscarriage (MIN - MAX)

0.20 (0.18–0.22)

0.00 (0.00–0.00)

Transition probabilities valid for all the sample

 Cycle with embryo freezing (MIN - MAX)

0.30 (0.27–0.33)

0.30 (0.27–0.33)

 

Expert opinion

 Cycle without embryo freezing (MIN - MAX)

0.40 (0.36–0.44)

0.40 (0.36–0.44)

 

Expert opinion

 Dropout (MIN - MAX)

0.30 (0.27–0.33)

0.30 (0.27–0.33)

 

Expert opinion