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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: Melatonin inhibits 17β-estradiol-induced migration, invasion and epithelial-mesenchymal transition in normal and endometriotic endometrial epithelial cells

Fig. 5

Melatonin reverses 17β-estradiol-induced EMT in EEC involving Notch1 signaling pathway. EEC were treated with different drugs for 72 h. a The protein expression levels of Notch1 (NICD), E-cadherin, N-cadherin, Vimentin, Slug, Snail, Numb and Actin were determined by western blot. β-actin was used as a loading control. b The ratios of Notch1/E-cadherin/N-cadherin/Vimentin/Slug/Snail/Numb to β-actin were analyzed. Data are presented as the mean ± SD. E2: 17β-estradiol; MLT: melatonin. *p < 0.05, ** p < 0.01 vs. untreated cells. #p < 0.05, ##p < 0.01 vs. E2-treated cells

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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