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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Melatonin inhibits 17β-estradiol-induced migration, invasion and epithelial-mesenchymal transition in normal and endometriotic endometrial epithelial cells

Fig. 3

Melatonin abolishes 17β-estradiol-induced migration and invasion in EEC. a: Transwell migration assays of EEC after treatment. EEC were treated with MLT, DAPT, or E2 with or without MLT/DAPT b: Transwell invasion assays of EEC after treatment. Representative images were obtained at 200× magnification. Graphs show the relative number of migrating and invading cells for each treatment group (averaged across four random images). Scale bar: 50 μm. Data are presented as the mean ± SD. E2: 17β-estradiol; MLT: melatonin. *p < 0.05, ** p < 0.01 vs. untreated cells. #p < 0.05, ##p < 0.01 vs. E2-treated cells

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