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Table 3 Pregnancy and live birth outcomes after FET

From: Progestin-primed milder stimulation with clomiphene citrate yields fewer oocytes and suboptimal pregnancy outcomes compared with the standard progestin-primed ovarian stimulation in infertile women with polycystic ovarian syndrome

 

Study group

(HMG/MPA/CC)

Control group

(HMG/MPA)

Risk Ratio (95% CI)

P value

Rates per embryo transfer

 Clinical pregnancy rate

73.9%(88/119)

62.5%(105/168)

1.70 (1.02, 2.85)

0.042

 Implantation rate

52.2%(119/228)

42.7%(140/328)

1.47(1.04, 2.06)

0.027

 Ectopic pregnancy rate

1.1%(1/88)

1.9%(2/105)

0.59(0.05, 6.64)

0.667

Miscarriage rate

 Early miscarriage

9.1%(8/88)

12.4%(13/105)

0.71(0.28,1.79)

0.465

 Later miscarriage

6.8%(6/88)

5.7%(6/105)

1.21(0.38,3.89)

0.752

 Ongoing pregnancy rate

66.4%(79/119)

53.6%(90/168)

1.71(1.05,2.78)

0.030

 Live-birth rate

59.7%(71/119)a

49.4%(83/168)a

1.52(0.94,2.44)

0.086

Rates per participant

 Ongoing pregnancy rate

71.8%(79/110)

81.8%(90/110)

0.57(0.30,1.07)

0.079

 Live birth rate

64.5%(71/110)a

75.5%(83/110)a

0.59(0.33,1.06)

0.077

Newborns

 Single birth (n)

50

60

  

 Single birthweight (g)

3270.4 ± 644.9

3357.0 ± 437.1

 

0.422

 Twin birth (n)

21

23

  

 Twin birthweight (g)

2371.7 ± 460.7

2460.0 ± 423.5

 

0.497

  1. a3 pregnant women lost to follow up to live birth (2 in study group and 1 in control group)