TY - JOUR AU - González, R. R. AU - Simón, C. AU - Caballero-Campo, P. AU - Norman, R. AU - Chardonnens, D. AU - Devoto, L. AU - Bischof, P. PY - 2000 DA - 2000// TI - Leptin and reproduction JO - Hum Reprod Update VL - 6 UR - https://doi.org/10.1093/humupd/6.3.290 DO - 10.1093/humupd/6.3.290 ID - González2000 ER - TY - JOUR AU - Zhou, Y. AU - Rui, L. PY - 2013 DA - 2013// TI - Leptin signaling and leptin resistance JO - Front Med VL - 7 UR - https://doi.org/10.1007/s11684-013-0263-5 DO - 10.1007/s11684-013-0263-5 ID - Zhou2013 ER - TY - JOUR AU - Ahima, R. S. PY - 2006 DA - 2006// TI - Adipose tissue as an endocrine organ JO - Obesity VL - 14 UR - https://doi.org/10.1038/oby.2006.317 DO - 10.1038/oby.2006.317 ID - Ahima2006 ER - TY - JOUR AU - Barash, I. A. AU - Cheung, C. C. AU - Weigle, D. S. AU - Ren, H. AU - Kabigting, E. B. AU - Kuijper, J. L. AU - Clifton, D. K. AU - Steiner, R. A. PY - 1996 DA - 1996// TI - Leptin is a metabolic signal to the reproductive system JO - Endocrinology VL - 137 UR - https://doi.org/10.1210/endo.137.7.8770941 DO - 10.1210/endo.137.7.8770941 ID - Barash1996 ER - TY - JOUR AU - Mounzih, K. AU - Lu, R. AU - Chehab, F. F. PY - 1997 DA - 1997// TI - Leptin treatment rescues the sterility of genetically obese Ob/Ob males JO - Endocrinology VL - 138 UR - https://doi.org/10.1210/endo.138.3.5024 DO - 10.1210/endo.138.3.5024 ID - Mounzih1997 ER - TY - JOUR AU - Considine, R. V. AU - Sinha, M. K. AU - Heiman, M. L. AU - Kriauciunas, A. AU - Stephens, T. W. AU - Nyce, M. R. PY - 1996 DA - 1996// TI - Serum immunoreactive-leptin concentrations in normal-weight and obese humans JO - N Engl J Med VL - 334 UR - https://doi.org/10.1056/NEJM199602013340503 DO - 10.1056/NEJM199602013340503 ID - Considine1996 ER - TY - JOUR AU - Handjieva-Darlenska, T. AU - Boyadjieva, N. PY - 2009 DA - 2009// TI - The effect of high-fat diet on plasma ghrelin and leptin levels in rats JO - J Physiol Biochem VL - 65 UR - https://doi.org/10.1007/BF03179066 DO - 10.1007/BF03179066 ID - Handjieva-Darlenska2009 ER - TY - JOUR AU - Leisegang, K. AU - Bouic, P. J. AU - Menkveld, R. AU - Henkel, R. R. PY - 2014 DA - 2014// TI - Obesity is associated with increased seminal insulin and leptin alongside reduced fertility parameters in a controlled male cohort JO - Reprod Biol Endocrinol VL - 12 UR - https://doi.org/10.1186/1477-7827-12-34 DO - 10.1186/1477-7827-12-34 ID - Leisegang2014 ER - TY - JOUR AU - Einollahi, N. AU - Dashti, N. AU - Emamgholipour, S. AU - Zarebavani, M. AU - Sedighi-Gilani, M. A. AU - Choobineh, H. PY - 2016 DA - 2016// TI - Evidence for alteration in serum concentrations of leptin in infertile men categorized based on BMI JO - Clin Lab VL - 59 ID - Einollahi2016 ER - TY - JOUR AU - Hofny, E. R. AU - Ali, M. E. AU - Abdel-Hafez, H. Z. AU - Eel-D, K. AU - Mohamed, E. E. AU - Abd El-Azeem, H. G. AU - Mostafa, T. PY - 2010 DA - 2010// TI - Semen parameters and hormonal profile in obese fertile and infertile males JO - Fertil Steril VL - 94 UR - https://doi.org/10.1016/j.fertnstert.2009.03.085 DO - 10.1016/j.fertnstert.2009.03.085 ID - Hofny2010 ER - TY - JOUR AU - Steinman, N. AU - Gamzu, R. AU - Yogev, L. AU - Botchan, A. AU - Schreiber, L. AU - Yavetz, H. PY - 2001 DA - 2001// TI - Serum leptin concentrations are higher in azoospermic than in normozoospermic men JO - Fertil Steril VL - 75 UR - https://doi.org/10.1016/S0015-0282(01)01707-1 DO - 10.1016/S0015-0282(01)01707-1 ID - Steinman2001 ER - TY - JOUR AU - Yuan, M. AU - Huang, G. AU - Li, J. AU - Zhang, J. AU - Li, F. AU - Li, K. PY - 2014 DA - 2014// TI - Hyperleptinemia directly affects testicular maturation at different sexual stages in mice, and suppressor of cytokine signaling 3 is involved in this process JO - Reprod Biol Endocrinol VL - 12 UR - https://doi.org/10.1186/1477-7827-12-15 DO - 10.1186/1477-7827-12-15 ID - Yuan2014 ER - TY - JOUR AU - Giovambattista, A. AU - Suescun, M. O. AU - Nessralla, C. C. AU - França, L. R. AU - Spinedi, E. AU - Calandra, R. S. PY - 2003 DA - 2003// TI - Modulatory effects of leptin on leydig cell function of normal and hyperleptinemia rats JO - Neuroendocrinology VL - 78 UR - https://doi.org/10.1159/000074448 DO - 10.1159/000074448 ID - Giovambattista2003 ER - TY - JOUR AU - Haron, M. N. AU - D'Souza, U. J. AU - Jaafar, H. AU - Zakaria, R. AU - Singh, H. J. PY - 2010 DA - 2010// TI - Exogenous leptin administration decreases sperm count and increases the fraction of abnormal sperm in adult rats JO - Fertil Steril VL - 93 UR - https://doi.org/10.1016/j.fertnstert.2009.07.995 DO - 10.1016/j.fertnstert.2009.07.995 ID - Haron2010 ER - TY - JOUR AU - Abbasihormozi, S. AU - Shahverdi, A. AU - Kouhkan, A. AU - Cheraghi, J. AU - Akhlaghi, A. A. AU - Kheimeh, A. PY - 2013 DA - 2013// TI - Relationship of leptin administration with production of reactive oxygen species, sperm DNA fragmentation, sperm parameters and hormone profile in the adult rat JO - Arch Gynecol Obstet VL - 287 UR - https://doi.org/10.1007/s00404-012-2675-x DO - 10.1007/s00404-012-2675-x ID - Abbasihormozi2013 ER - TY - JOUR AU - Almabhouh, F. A. AU - Osman, K. AU - Ibrahim, S. F. AU - Gupalo, S. AU - Gnanou, J. AU - Ibrahim, E. AU - Singh, H. J. PY - 2016 DA - 2016// TI - Melatonin ameliorates the adverse effects of leptin on sperm JO - Asian J Androl VL - 19 ID - Almabhouh2016 ER - TY - JOUR AU - Almabhouh, F. A. AU - Singh, H. J. PY - 2018 DA - 2018// TI - Adverse effects of leptin on histone- to- protamine transition during spermatogenesis are prevented by melatonin in Sprague- Dawley rats JO - Andrologia VL - 50 UR - https://doi.org/10.1111/and.12814 DO - 10.1111/and.12814 ID - Almabhouh2018 ER - TY - JOUR AU - Fernandez, C. D. AU - Fernandes, G. S. AU - Favareto, A. P. AU - Perobelli, J. E. AU - Sanabria, M. AU - Kempinas, W. D. PY - 2017 DA - 2017// TI - Decreased implantation number after in utero artificial insemination can reflect an impairment of fertility in adult male rats after exogenous leptin exposure JO - Reprod Sci VL - 24 UR - https://doi.org/10.1177/1933719116653678 DO - 10.1177/1933719116653678 ID - Fernandez2017 ER - TY - JOUR AU - Almabhouh, F. A. AU - Osman, K. AU - Siti Fatimah, I. AU - Sergey, G. AU - Gnanou, J. AU - Singh, H. J. PY - 2015 DA - 2015// TI - Effects of leptin on sperm count and morphology in Sprague-Dawley rats and their reversibility following a 6-week recovery period JO - Andrologia VL - 47 UR - https://doi.org/10.1111/and.12325 DO - 10.1111/and.12325 ID - Almabhouh2015 ER - TY - JOUR AU - Kim, C. Y. AU - Kim, K. H. PY - 2014 DA - 2014// TI - Curcumin prevents leptin-induced tight junction dysfunction in intestinal Caco-2 BBe cells JO - J Nutr Biochem VL - 25 UR - https://doi.org/10.1016/j.jnutbio.2013.08.011 DO - 10.1016/j.jnutbio.2013.08.011 ID - Kim2014 ER - TY - JOUR AU - Le Dréan, G. AU - Haure-Mirande, V. AU - Ferrier, L. AU - Bonnet, C. AU - Hulin, P. AU - de Coppet, P. AU - Segain, J. P. PY - 2014 DA - 2014// TI - Visceral adipose tissue and leptin increase colonic epithelial tight junction permeability via a RhoA-ROCK-dependent pathway JO - FASEB J VL - 28 UR - https://doi.org/10.1096/fj.13-234203 DO - 10.1096/fj.13-234203 ID - Le Dréan2014 ER - TY - JOUR AU - Le Dréan, G. AU - Segain, J. P. PY - 2014 DA - 2014// TI - Connecting metabolism to intestinal barrier function: the role of leptin JO - Tissue Barriers VL - 2 UR - https://doi.org/10.4161/21688362.2014.970940 DO - 10.4161/21688362.2014.970940 ID - Le Dréan2014 ER - TY - JOUR AU - Cheng, C. Y. AU - Mruk, D. D. PY - 2012 DA - 2012// TI - The blood-testis barrier and its implications for male contraception JO - Pharmacol Rev VL - 64 UR - https://doi.org/10.1124/pr.110.002790 DO - 10.1124/pr.110.002790 ID - Cheng2012 ER - TY - JOUR AU - Mruk, D. D. AU - Cheng, C. Y. PY - 2004 DA - 2004// TI - Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis JO - Endocr Rev VL - 25 UR - https://doi.org/10.1210/er.2003-0022 DO - 10.1210/er.2003-0022 ID - Mruk2004 ER - TY - JOUR AU - Morrow, C. M. AU - Mruk, D. AU - Cheng, C. Y. AU - Hess, R. A. PY - 2010 DA - 2010// TI - Claudin and occludin expression and function in the seminiferous epithelium JO - Philos Trans R Soc Lond Ser B Biol Sci VL - 365 UR - https://doi.org/10.1098/rstb.2010.0025 DO - 10.1098/rstb.2010.0025 ID - Morrow2010 ER - TY - JOUR AU - Cao, X. N. AU - Shen, L. J. AU - Wu, S. D. AU - Yan, C. AU - Zhou, Y. AU - Xiong, G. PY - 2017 DA - 2017// TI - Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testis barrier (BTB) integrity JO - Toxicol Lett VL - 266 UR - https://doi.org/10.1016/j.toxlet.2016.12.004 DO - 10.1016/j.toxlet.2016.12.004 ID - Cao2017 ER - TY - JOUR AU - Zhang, J. AU - Li, Z. AU - Qie, M. AU - Zheng, R. AU - Shetty, J. AU - Wang, J. PY - 2016 DA - 2016// TI - Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice JO - Food Chem Toxicol VL - 94 UR - https://doi.org/10.1016/j.fct.2016.05.017 DO - 10.1016/j.fct.2016.05.017 ID - Zhang2016 ER - TY - JOUR AU - Qiu, L. AU - Zhang, X. AU - Zhang, X. AU - Zhang, Y. AU - Gu, J. AU - Chen, M. PY - 2013 DA - 2013// TI - Sertoli cell is a potential target for perfluorooctane sulfonate-induced reproductive dysfunction in male mice JO - Toxicol Sci VL - 135 UR - https://doi.org/10.1093/toxsci/kft129 DO - 10.1093/toxsci/kft129 ID - Qiu2013 ER - TY - JOUR AU - Ahn, J. H. AU - Choi, Y. S. AU - Choi, J. H. PY - 2015 DA - 2015// TI - Leptin promotes human endometriotic cell migration and invasion by up-regulating MMP-2 through the JAK2/STAT3 signaling pathway JO - Mol Hum Reprod VL - 21 UR - https://doi.org/10.1093/molehr/gav039 DO - 10.1093/molehr/gav039 ID - Ahn2015 ER - TY - JOUR AU - Rossi, S. P. AU - Windschüttl, S. AU - Matzkin, M. E. AU - Rey-Ares, V. AU - Terradas, C. AU - Ponzio, R. PY - 2016 DA - 2016// TI - Reactive oxygen species (ROS) production triggered by prostaglandin D2 (PGD2) regulates lactate dehydrogenase (LDH) expression/activity in TM4 Sertoli cells JO - Mol Cell Endocrinol VL - 434 UR - https://doi.org/10.1016/j.mce.2016.06.021 DO - 10.1016/j.mce.2016.06.021 ID - Rossi2016 ER - TY - JOUR AU - Choi, M. S. AU - Park, H. J. AU - Oh, J. H. AU - Lee, E. H. AU - Park, S. M. AU - Yoon, S. PY - 2014 DA - 2014// TI - Nonylphenol-induced apoptotic cell death in mouse TM4 Sertoli cells via the generation of reactive oxygen species and activation of the ERK signaling pathway JO - J Appl Toxicol VL - 34 UR - https://doi.org/10.1002/jat.2886 DO - 10.1002/jat.2886 ID - Choi2014 ER - TY - BOOK PY - 2010 DA - 2010// TI - WHO laboratory manual for the examination and processing of human semen PB - World Health Organization CY - Geneva ID - ref32 ER - TY - JOUR AU - Ward, M. A. PY - 2005 DA - 2005// TI - Intracytoplasmic sperm injection effects in infertile azh mutant mice JO - Biol Reprod VL - 73 UR - https://doi.org/10.1095/biolreprod.105.040675 DO - 10.1095/biolreprod.105.040675 ID - Ward2005 ER - TY - JOUR AU - Meng, J. AU - Holdcraft, R. W. AU - Shima, J. E. AU - Griswold, M. D. AU - Braun, R. E. PY - 2005 DA - 2005// TI - Androgens regulate the permeability of the blood–testis barrier JO - Proc Natl Acad Sci VL - 102 UR - https://doi.org/10.1073/pnas.0506084102 DO - 10.1073/pnas.0506084102 ID - Meng2005 ER - TY - JOUR AU - El-Hefnawy, T. AU - Ioffe, S. AU - Dym, M. PY - 2000 DA - 2000// TI - Expression of the leptin receptor during germ cell development in the mouse testis JO - Endocrinology VL - 141 UR - https://doi.org/10.1210/endo.141.7.7542 DO - 10.1210/endo.141.7.7542 ID - El-Hefnawy2000 ER - TY - JOUR AU - Woods, D. C. AU - White, Y. A. AU - Niikura, Y. AU - Kiatpongsan, S. AU - Lee, H. J. AU - Tilly, J. L. PY - 2013 DA - 2013// TI - Embryonic stem cell–derived granulosa cells participate in ovarian follicle formation in vitro and in vivo JO - Reprod Sci VL - 20 UR - https://doi.org/10.1177/1933719113483017 DO - 10.1177/1933719113483017 ID - Woods2013 ER - TY - JOUR AU - Hoffmann, A. AU - Manjowk, G. M. AU - Wagner, I. V. AU - Klöting, N. AU - Ebert, T. AU - Jessnitzer, B. PY - 2016 DA - 2016// TI - Leptin within the subphysiological to physiological range dose-dependently improves male reproductive function in an obesity mouse model JO - Endocrinology VL - 157 UR - https://doi.org/10.1210/en.2015-1966 DO - 10.1210/en.2015-1966 ID - Hoffmann2016 ER - TY - JOUR AU - Fan, Y. AU - Liu, Y. AU - Xue, K. AU - Gu, G. AU - Fan, W. AU - Xu, Y. AU - Ding, Z. PY - 2015 DA - 2015// TI - Diet-induced obesity in male C57BL/6 mice decreases fertility as a consequence of disrupted blood-testis barrier JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0120775 DO - 10.1371/journal.pone.0120775 ID - Fan2015 ER - TY - JOUR AU - Tena-Sempere, M. AU - Manna, P. R. AU - Zhang, F. P. AU - Pinilla, L. AU - González, L. C. AU - Diéguez, C. AU - Huhtaniemi, I. AU - Aguilar, E. PY - 2001 DA - 2001// TI - Molecular mechanisms of leptin action in adult rat testis: potential targets for leptin-induced inhibition of steroidogenesis and pattern of leptin receptor messenger ribonucleic acid expression JO - J Endocrinol VL - 170 UR - https://doi.org/10.1677/joe.0.1700413 DO - 10.1677/joe.0.1700413 ID - Tena-Sempere2001 ER - TY - JOUR AU - Martins, A. D. AU - Moreira, A. C. AU - Sá, R. AU - Monteiro, M. P. AU - Sousa, M. AU - Carvalho, R. A. PY - 2015 DA - 2015// TI - Leptin modulates human Sertoli cell acetate production and glycolytic profile: a novel mechanism of obesity-induced male infertility? JO - Biochim Biophys Acta VL - 1852 UR - https://doi.org/10.1016/j.bbadis.2015.06.005 DO - 10.1016/j.bbadis.2015.06.005 ID - Martins2015 ER - TY - JOUR AU - Peelman, F. AU - Zabeau, L. AU - Moharana, K. AU - Savvides, S. N. AU - Tavernier, J. PY - 2014 DA - 2014// TI - 20 years of leptin: insights into signaling assemblies of the leptin receptor JO - J Endocrinol VL - 223 UR - https://doi.org/10.1530/JOE-14-0264 DO - 10.1530/JOE-14-0264 ID - Peelman2014 ER - TY - JOUR AU - Wu, D. AU - Huang, C. J. AU - Khan, F. A. AU - Jiao, X. F. AU - Liu, X. M. AU - Pandupuspitasari, N. S. AU - Brohi, R. D. AU - Huo, L. J. PY - 2017 DA - 2017// TI - SENP3 grants tight junction integrity and cytoskeleton architecture in mouse Sertoli cells JO - Oncotarget VL - 8 ID - Wu2017 ER - TY - JOUR AU - Donahoo, W. T. AU - Stob, N. R. AU - Ammon, S. AU - Levin, N. AU - Eckel, R. H. PY - 2011 DA - 2011// TI - Leptin increases skeletal muscle lipoprotein lipase and postprandial lipid metabolism in mice JO - Metabolism VL - 60 UR - https://doi.org/10.1016/j.metabol.2010.03.016 DO - 10.1016/j.metabol.2010.03.016 ID - Donahoo2011 ER - TY - JOUR AU - Burnett, L. C. AU - Skowronski, A. A. AU - Rausch, R. AU - LeDuc, C. A. AU - Leibel, R. L. PY - 2017 DA - 2017// TI - Determination of the half-life of circulating leptin in the mouse JO - Int J Obes VL - 41 UR - https://doi.org/10.1038/ijo.2016.238 DO - 10.1038/ijo.2016.238 ID - Burnett2017 ER - TY - JOUR AU - Luukkaa, V. AU - Pesonen, U. AU - Huhtaniemi, I. AU - Lehtonen, A. AU - Tilvis, R. AU - Tuomilehto, J. AU - Koulu, M. AU - Huupponen, R. PY - 1998 DA - 1998// TI - Inverse correlation between serum testosterone and leptin in men JO - J Clin Endocrinol Metab VL - 83 ID - Luukkaa1998 ER - TY - JOUR AU - Söderberg, S. AU - Olsson, T. AU - Eliasson, M. AU - Johnson, O. AU - Brismar, K. AU - Carlström, K. AU - Ahrén, B. PY - 2001 DA - 2001// TI - A strong association between biologically active testosterone and leptin in non-obese men and women is lost with increasing (central) adiposity JO - Int J Obes Relat Metab Disord VL - 25 UR - https://doi.org/10.1038/sj.ijo.0801467 DO - 10.1038/sj.ijo.0801467 ID - Söderberg2001 ER - TY - JOUR AU - Vigueras-Villaseñor, R. M. AU - Rojas-Castañeda, J. C. AU - Chávez-Saldaña, M. AU - Gutiérrez-Pérez, O. AU - García-Cruz, M. E. AU - Cuevas-Alpuche, O. PY - 2011 DA - 2011// TI - Alterations in the spermatic function generated by obesity in rats JO - Acta Histochem VL - 113 UR - https://doi.org/10.1016/j.acthis.2009.10.004 DO - 10.1016/j.acthis.2009.10.004 ID - Vigueras-Villaseñor2011 ER - TY - JOUR AU - Landry, D. A. AU - Sormany, F. AU - Haché, J. AU - Roumaud, P. AU - Martin, L. J. PY - 2017 DA - 2017// TI - Steroidogenic genes expressions are repressed by high levels of leptin and the JAK/STAT signaling pathway in MA-10 Leydig cells JO - Mol Cell Biochem VL - 433 UR - https://doi.org/10.1007/s11010-017-3017-x DO - 10.1007/s11010-017-3017-x ID - Landry2017 ER -