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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: GnRH dysregulation in polycystic ovarian syndrome (PCOS) is a manifestation of an altered neurotransmitter profile

Fig. 5

Status of neurotransmitter degrading enzymes in PCOS rats. Enzyme activity of a monoamine oxidase A (MAOA) and b MAOB in various tissues of control and PCOS rats. c Bar graph represents values of mean fold change in gene expression of Catechol-O-methyl transferase (COMT) in PCOS animals as compared to control rats (represented by black dashed line). β-Actin was used as internal control for mRNA studies and fold change in expression was calculated by 2-ΔΔCT method. Activity of d acetylcholine esterase (AChE) and e glutamate dehydrogenase (GDH) in tissues of control and PCOS animals. Error bars represent SEM; n = 6 per group; *P < 0.05; **P < 0.01; ***P < 0.001 as compared to control group

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