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Table 2 Outcomes of COH

From: Pregnancy outcomes of PCOS overweight/obese patients after controlled ovarian stimulation with the GnRH antagonist protocol and frozen embryo transfer

 

Normal

Overweight/obese

P

Subjects, n

260

138

OHSS, n (%)

7 (2.7)

2 (1.4)

0.725

ICSI, n (%)

17 (6.5)

5 (3.6)

0.258

Ovarian stimulation, d

10.3 ± 2.3

11.2 ± 3.2

0.003

Gn dose, IU

1416.9 ± 533.7

1952.7 ± 747.9

0.000

Gn dose per kg, IU

26.8 ± 9.4

29.2 ± 11.0

0.023

GnRH-ant dose, mg

1.5 ± 0.6

1.5 ± 0.7

0.493

On hCG trigger day

 Follicles, na

2.9 ± 3.9

2.6 ± 3.7

0.528

 Estradiol, pmol/L

17,576.9 ± 2005.3

16,804.5 ± 3153.0

0.001

 LH, U/L

2.1 ± 4.8

2.8 ± 4.5

0.061

 Prolactin, nmol/L

3.9 ± 3.2

3.8 ± 2.3

0.655

 Endometrial thickness, mm

9.7 ± 2.0

9.7 ± 2.4

0.418

Before FET

 Estradiol, pmol/L

2365.5 ± 1646.2

1924.7 ± 1484.8

0.010

 LH, U/L

9.3 ± 6.9

8.3 ± 8.1

0.222

 Prolactin, nmol/L

1.2 ± 2.6

1.1 ± 2.3

0.615

 Endometrial thickness, mm

8.8 ± 6.9

8.4 ± 1.6

0.878

Oocytes retrieved, n

23.0 ± 9.8

22.1 ± 9.7

0.562

Good-quality embryos on day 3, n

4.5 ± 3.8

3.9 ± 3.4

0.113

Embryos transferred, n (%)

 Day 3

56 (21.5)

32 (23.4)

0.786

 Day 4

7 (2.7)

6 (4.4)

 

 Day 5

173 (66.5)

87 (63.5)

 

 Day 6

24 (9.2)

12 (8.8)

 

Embryos successfully transferred, n (%)

 One

23 (8.8)

16 (11.6)

0.381

 Two

237 (91.2)

122 (88.4)

 
  1. LH Luteinizing hormone, OHSS ovarian hyperstimulation syndrome
  2. aFollicles > 18 mm