Table 2 The clinical and laboratory parameters of obese and lean patients with or without PCOS
Obese PCOS n = 30 | Lean PCOS n = 31 | Obese Control n = 30 | Lean Control n = 33 | p value | |
|---|---|---|---|---|---|
Age (year) | 24.6 ± 4.6 | 24.7 ± 4.9 | 23.4 ± 4.3 | 26.9 ± 5.3 | 0.059 |
Body mass index (kg/m2) | 29.1 ± 4.2 a,c | 22.3 ± 3.7 d | 31.1 ± 4.6 f | 21.4 ± 2.8 | < 0.001 |
Waist to hip ratio (WHR) (cm) | 0.85 ± 0.06 a,b,c | 0.75 ± 0.04 d,e | 0.80 ± 0.06 f | 0.73 ± 0.03 | < 0.001 |
Ferriman–Gallwey score | 7 (3-17) a,b,c | 4 (2-13) d,e | 2 (1-5) | 1 (1-4) | < 0.001 |
Systolic blood pressure (mmHg) | 120 (90-150) a,c | 110 (90-130) | 110 (100-130) | 110 (90-120) | 0.011 |
Diastolic blood pressure (mmHg) | 80 (60-110) a,b,c | 70 (60-80) | 70 (60-80) | 70 (60-80) | 0.006 |
Glucose (mg/dl) | 92 (74-123) a,b,c | 83 (64-112) | 85 (65-110) | 78 (61-98) | 0.007 |
HOMA-IR | 3.5 (1.4-13.8) a,b,c | 2.2 (0.6-9.8)d,e | 2.6 (1.1-8.8) f | 1.2 (0.4-5.6) | < 0.001 |
hsCRP (mg/l) | 4.1(1.2-29.1) a,b,c | 1.5 (0.3-8.8) e | 2.7 (0.9-7.8) f | 0.9 (0.2-3.5) | < 0.001 |
Leucocytes (/mm3) | 8.9 ± 2.3 a,c | 6.9 ± 1.8 d | 7.8 ± 2.6 | 6.2 ± 1.4 | < 0.001 |
Neutrophil (/mm3) | 5.1 ± 1.9 c | 4.5 ± 1.3 e | 4.5 ± 1.4 | 3.7 ± 1.2 | 0.005 |
Lymphocytes (/mm3) | 2.3 ± 0.7 | 2.1 ± 0.6 | 2.5 ± 0.8 | 2.5 ± 0.7 | 0.158 |
Monocyte (/mm3) | 657.7 ± 259.3 b,c | 634.6 ± 139.1 d,e | 517.4 ± 184.9 | 504.7 ± 187.9 | 0.005 |
Trigliserid (mg/dL) | 145.5(46.0-529.0) a,c | 69.0 (53.0-136.0) d | 116.0 (58.0-280.0) f | 64.0 (44.0-170.0) | < 0.001 |
Total cholesterol (mg/dL) | 189.6 ± 32.1 a,b | 164.1 ± 27.5 | 167.1 ± 26.2 | 172.2 ± 30.3 | 0.005 |
LDL (mg/dL) | 110.7 ± 30.5 b,c | 95.7 ± 34.6 | 94.9 ± 22.7 | 87.8 ± 26.5 | 0.015 |
HDL (mg/dL) | 43.6 ± 8.9 a,b,c | 51.2 ± 11.3 e | 54.5 ± 9.9 f | 62.8 ± 14.6 | < 0.001 |
Total testosteron (ng/dl) | 1.40 (0.32-4.71) a,b,c | 1.04 (0.12-2.80) d,e | 0.58 (0.07-0.98) f | 0.11 (0.07-0.25) | < 0.001 |
FSH (IU/L) | 5.75 ± 1.24 | 5.97 ± 1.49 | 6.22 ± 1.60 | 6.46 ± 1.77 | 0.302 |
LH (IU/L) | 9.80 (5.03-22.1) b,c | 9.15 (5.50-14.5) d,e | 6.88 (4.76-14.6) f | 5.70 (4.72-10.01) | < 0.001 |
Estradiol (pg/ml) | 47.37 ± 22.64 | 43.35 ± 18.44 | 43.26 ± 21.03 | 41.60 ± 19.47 | 0.297 |
TSH (mIU/L) | 2.03 ± 1.27 | 2.27 ± 1.07 | 1.92 ± 0.91 | 2.22 ± 1.13 | 0.564 |
Prolaktin (ng/ml) | 16.42 ± 7.68 | 18.22 ± 8.42 | 15.65 ± 6.72 | 17.15 ± 6.10 | 0.442 |
Monocytes to HDL ratio | 15.6 (3.7-30.5) a,b,c | 9.6 (5.4-24.7) e | 9.9 (3.8-20.9) f | 7.9 (3.3-24.2) | < 0.001 |