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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: Efficacy, safety and recurrence of new progestins and selective progesterone receptor modulator for the treatment of endometriosis: a comparison study in mice

Fig. 2

Comparisons of anti-endometriosis mechanism of Esmya, Duphaston and Dienogest. Relative mRNA expression of a-c, adhesion (Mmp2 and Itgav β3) and invasion (Plau) marker genes, d-f, apoptosis-related genes (Mapk1, NF-kB p105 and pro-Caspase 3), g-i, angiogenesis and proliferation mrakers (Vegf, Hif1α and Pcna) and j-k, hormone receptors (ERα/ERβ ratio and PR) in lesions; and ELISA quantitation of l, Prostaglandin E2 (PGE2) concentrations in peritoneal fluid. Data are shown as mean ± SEM, n = 9 for each group, *: p < 0.05 when compared to the control group

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