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Table 4 The mean percentage of gene methylation among groups

From: ART manipulation after controlled ovarian stimulation may not increase the risk of abnormal expression and DNA methylation at some CpG sites of H19,IGF2 and SNRPN in foetuses: a pilot study

Mean value of methylation (%)

Group 1 (n = 3)

Group 2 (n = 3)

Group 3 (n = 3)

Group 4 (n = 3)

Group 5 (n = 3)

Group 6 (n = 3)

H19

38.21 ± 7.10

36.58 ± 6.66

37.79 ± 8.84

38.96 ± 7.37

32.67 ± 11.91

39.21 ± 7.10

IGF2

1.87 ± 1.25

3.73 ± 2.22

3.73 ± 2.96

2.33 ± 1.29

3.07 ± 3.63

1.93 ± 0.59

SNRPN

45.96 ± 5.47

47.67 ± 2.77

47.19 ± 3.01

46.93 ± 3.52

46.63 ± 3.83

47.44 ± 3.50

  1. Group 1: multifoetal reduction after IVF fresh transferred D3 embryos (n = 3); Group 2: multifoetal reduction after IVF frozen transferred D3 embryos (n = 3); Group 3: multifoetal reduction after IVF frozen transferred D5 embryos (n = 3); Group 4: multifoetal reduction after ICSI fresh transferred D3 embryos (n = 3); Group 5: multifoetal reduction after ICSI frozen transferred D3 embryos (n = 3); Group 6: multifoetal reduction after controlled ovarian stimulation (COS) (n = 3)