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Table 3 ART cycle stimulation parameters and embryology outcomes

From: Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial

Variable Study group (n = 76) Control group (n = 93) p- value
Cycle stimulation
Total dose of Gn (IU), median (IQR) 2000 (1200, 4275) 3075 (1900, 4275) 0.03
Duration of stimulation (days), median (IQR) 10 (9, 11) 11 (9, 12) 0.08
Peak E2 concentration (pmol/l), median (IQR) 2349 (892, 4784) 1685 (1125, 3042) 0.02
Endometrial thickness on the day of hCG trigger (mm), mean ± SD 10.12 ± 1.93 10.34 ± 1.50 0.13
Patients who had oocyte retrieval 72/76 (94.74) 83/93 (89.25) 0.82
Cancelled cycles a, n (%) 4/76 (5.23) 10/93 (10.75) 0.27
Embryology outcomes
Retrieved oocytes, median (IQR) 4 (2, 5) 2 (1, 4) 0.002
ICSI cycles, n (%) 24/76 (31.58) 19/93 (20.43) 0.20
Fertilized oocytes (2PN), median (IQR) 0.80 (0.50, 0.93) 0.50 (0.33, 1.0) 0.01
Fertilization rate b, n (%) 191/253 (67.49) 191/283 (45.06) 0.001
Number of high quality embryos, median (IQR) 1 (0, 2) 0 (0, 1.75) 0.03
  1. aIncluded women in who did not respond to stimulation and did not have oocyte retrieval
  2. bCalculated as following: the number of total 2PN embryos divided by the number of total inseminated oocytes
  3. E2 – estradiol; Gn – gonadotrophin; hCG – human chorionic gonadotrophin; IQR – interquartile range; LH - luteinizing hormone; P - progesterone, 2PN – two pronuclear, SD - standard deviation