Fig. 1
From: The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
Cell viability (a), testosterone (b) and progesterone concentration (c) results for TM3 cell exposure to various concentrations of tumour necrosis factor-alpha (TNFα). All tested parameters significantly decreased for all concentrations of TNFα. For testosterone and progesterone results, ANOVA repeated measures analysis of variance was significant (P < 0.001), as was the one-way analysis of variance (P < 0.001)