Table 3 Patients´ characteristics and laboratory parameters in the mid-trimester cohort study
From: Is Afamin a novel biomarker for gestational diabetes mellitus? A pilot study
Parameter | Normal 75 g-oral glucose-tolerance-test (OGTT) n = 76 | Pathological 75 g-oral glucose-tolerance-test (OGTT) n = 29 | p-value |
|---|---|---|---|
Gestational age at 75 g-oral glucose-tolerance-test (OGTT) performance (days) | |||
Mean (± standard deviation, SD) | 189 (40) | 168 (43) | 0.06 |
Median (Interquartile range, IQR) | 189 (165–221) | 176 (151.25–200.00) | |
Maternal age (years) | |||
Mean (± SD) | 30.59 (5.08) | 35.00 (5.01) | < 0.001 |
Median (IQR) | 30.50 (27.50–34.00) | 37.00 (31.50–39.00) | |
Body-mass-index (kg/m2) | |||
Mean (± SD) | 28.35 (7.13) | 31.15 (8.56) | 0.08 |
Median (IQR) | 26.80 (23.40–32.00) | 29.30 (25.60–34.65) | |
Fasting Insulin (μlU/ml) | |||
Mean (± SD) | 9.68 (7.53) | 12.68 (7.94) | 0.02 |
Median (IQR) | 7.90 (4.40–12.25) | 10.00 (7.63–14.90) | |
1 h Insulin (μlU/ml) | |||
Mean (± SD) | 90.26 (54.17) | 110.45 (57.89) | 0.07 |
Median (IQR) | 76.30 (52.35–121.00) | 102.00 (68.23–123.50) | |
2 h Insulin (μlU/ml) | |||
Mean (± SD) | 69.76 (46.40) | 121.16 (54.21) | < 0.001 |
Median (IQR) | 58.15 (42.90–85.10) | 120.00 (84.63–148.25) | |
Fasting glucose (mg/dl) | |||
Mean (± SD) | 77.70 (5.68) | 83.79 (11.93) | 0.03 |
Median (IQR) | 77.00 (74.00–81.50) | 81.00 (73.75–93.25) | |
1 h glucose (mg/dl) | |||
Mean (± SD) | 135.25 (24.86) | 179.00 (25.97) | < 0.001 |
Median (IQR) | 136.50 (119–156.50) | 175.00 (161.00–189.25) | |
2 h glucose (mg/dl) | |||
Mean (± SD) | 105.04 (21.02) | 152.69 (26.02) | < 0.001 |
Median (IQR) | 101.50 (87.00–121.00) | 156.00 (148.25–170.25) | |
HOMA-IR | |||
Mean (± SD) | 1.90 (1.52) | 2.72 (1.96) | 0.01 |
Median (IQR) | 1.50 (0.80–2.45) | 2.20 (1.53–3.33) | |
Afamin (mg/l) | |||
Mean (± SD) | 157.90 (36.32) | 180.83 (41.21) | 0.003 |
Median (IQR) | 160.49 (142.63–177.33) | 180.20 (158.68–211.94) | |
Gestational age at parturition (days) | |||
Mean (± SD) | 259 (21) | 256 (22) | 0.38 |
Median (IQR) | 266 (249–273) | 263 (249–269) | |
Newborn weight (gram) | |||
Mean (± SD) | 2851 (786) | 2916 (821) | 0.71 |
Median (IQR) | 3075 (2465–3385) | 3170 (2496–3473) | |