Table 1 Major effects of adipokines in fertility of the obese woman
Adipokines | Serum Levels | Effects |
|---|---|---|
Leptin | ↑ | Inhibits insulin induced ovarian steroidogenesis Inibiths LH stimulated E2 production by the granulosa cells |
Adiponectin | ↓ | Plasma insulin levels increase |
Resistin | ↑ | Causes insulin resistance |
Visfatin | ↑ | Increased insulin sensitivity |
Omentin | ↓ | Increased insulin sensitivity |
Chemerin | ↑ | Negatively regulates FSH_induced follicular steroidogenesis |