Table 1 Sperm proteins with a significantly higher or lower expression in asthenozoospermia in different proteomic studies
From: Proteomic profile of human spermatozoa in healthy and asthenozoospermic individuals
Study | Method | Identified proteins | |
|---|---|---|---|
up-regulated in astheno | down-regulated in astheno | ||
Hashemitabar et al. | 2D electrophoresis MALDI-TOF-TOF analysis | CLU, KRT1, ASRGL1 | AKAP4, ODF2, TUBB2B, COX6B, GSTMu3, PHGPx, GAPD-S, VDAC2, HSPA2, HSPA9 and SPANXB |
Siva et al. | 2D PAGE MALDI MS/MS analysis | TRIS, GPK2, SCOT1, unidentified | TUBB2C, tektin 1, PSMA3, HSPA2 |
Martı’nez-Heredia et al. | 2D electrophoresis MS analysis | CLUpre, DLDpre, FHpre, HSPA2, IMPA1, PSMB3, SEMG1pre, TEX12, MPST/ECH1pre | ACTB, ANXA5, COX6B, histone H2A, PIP, PIPpre, calcium binding protein-S100A9 |
Shen et al. | 2D electrophoresis MALDI-TOF analysis | PIPpre, flagellin, GPX4, GAPDH | TEKT4, Lacto, ODF2, SPANXB, PGK2, GRP78, Hsp70, DJ-1, CAB2, Actin, Heat shock protein 70 testis variant |
Zhao et al. | 2D electrophoresis MALDI-TOF analysis | PGM2, TPI, GOT-1, ODF, GS, semenogelin I precursor | IDH-α, CA-II, GDI-1, MSS1 |