Gene / hormone |
CYP19A1
|
FSHR
|
LHCGR
|
RGS2
|
VNN2
| E2 | P4 |
---|
Control | 3.12 (± 0.31) | 34.70 (± 4.41) | 3.29 (± 0.46) | 5.56 (± 0.29) | 6.26 (± 0.39) | 23.72 (± 1.57) | 824.61 (± 84.99) |
L-lactate | 3.78 (± 0.85) | 49.10 (± 8.33) | 3.18 (± 0.94) | 5.78 (± 0.32) | 7.39 (± 1.11) | 32.31 (± 5.26) | 905.01 (± 47.03) |
P | 0.50 | 0.20 | 0.92 | 0.63 | 0.39 | 0.19 | 0.45 |
- GC were stimulated with 30 mM L-lactate or the vehicle control NaCl 24 h prior to the end of the culture period of 8 days. Transcript abundance (×10−3, normalized to the reference gene RPLP0) and hormone concentrations (in ng/ml) are shown as means (± SEM) of n = 3 replicates, P-values were calculated using the student’s t-test or Mann-Whitney Test