Parameters | PCOS | non-PCOS | P value | ||||
---|---|---|---|---|---|---|---|
 | Total | Lean | Overweight | Total | Lean | Overweight | (PCOS vs non-PCOS) |
N | 61 | 30 | 31 | 56 | 38 | 18 | Â |
Age, yrs | 26(21–31) | 24.5(21–31.25)d | 26(23–31) | 26(24–29) | 25.5(24–27) | 29.5(26.75–34)a | 0.415 |
BMI, kg/m2 | 24.98(21.7–26.98) | 21.7(19.41–23.3)d | 26.89(25.63–27.77)c,f | 22.06(21–24.91) | 21.59(20.41–22.11) | 27.48(24.91–27.85)a | 0.062 |
WHR | 0.87 ± 0.07 | 0.83 ± 0.07d | 0.91 ± 0.06 c,f | 0.85 ± 0.07 | 0.82 ± 0.06 | 0.9 ± 0.07a | 0.043 |
FAT% | 32.5(28.5–37.3) | 28.8(22.85–31.6)d | 37.55(35.88–41.55)c,f | 31.2(23.7–38.6) | 24.25(21.3–27.3) | 38.6(36.5–41.4)a | 0.772 |
AUCglucose | 10.69(9.38–12.54) | 9.77(7.89–11.79) | 11.63(10.49–13.06)c,f | 9.69(8.1–11.66) | 8.79(7.51–10.74) | 10.73(9.73–12.6)a | 0.018 |
AUCinsulin | 107.57(54.18–161.07) | 81.25(48.38–130.12) | 137.51(91.62–193.94)c,f | 73.46(45.57–114.58) | 68.93(44.48–98.54) | 83.72(43.96–137.69) | 0.017 |
HOMA-IR | 2.21(1.39–4.2) | 1.62(0.92–2.31)d | 3.47(2.14–4.96)c | 1.93(1.19–2.69) | 1.61(1–2.25) | 3.22(1.85–4.46)a | 0.066 |
Matsuda Index | 65.61(40.35–105.8) | 101.18(69.86–152.44) | 49.8(37.46–63.53)c,f | 100.13(63.46–154.98) | 110.19(86.21–166.93) | 70.21(42.8–113.74)a | 0.008 |
DI | 8.67(4.55–16.1) | 14.17(7.23–20.69)d | 6.14(2.37–9.79)c,f | 10.94(5.48–22.47) | 18.09(8.81–23.94) | 5.49(1.98–7.43)a | 0.213 |
TG, mmol/L | 1.17(0.8–1.53) | 0.87(0.72–1.18)d | 1.26(1.09–1.78)f | 1.29(0.77–1.6) | 1.07(0.66–1.6) | 1.48(1.15–1.93)a | 0.704 |
TC, mmol/L | 4.42(4.01–4.88) | 4.14(3.91–4.75)b,d | 4.6(4.01–5.18)c | 4.2(3.41–4.89) | 3.56(3.34–4.6) | 4.66(4.34–5.16)a | 0.024 |
HDL-C, mmol/L | 1.25(1.08–1.54) | 1.45(1.27–1.67)d | 1.18(1.02–1.25)c,f | 1.44(1.21–1.57) | 1.47(1.34–1.65) | 1.18(1.04–1.31)a | 0.218 |
LDL-C, mmol/L | 2.77 ± 0.83 | 2.49 ± 0.68d | 3.04 ± 0.89c,f | 2.55 ± 0.58 | 2.35 ± 0.53 | 2.96 ± 0.48a | 0.101 |
hsCRP, mg/L | 1.09(0.33–3.03) | 0.54(0.22–1.35)d | 2.04(0.55–4.15)c,f | 0.37(0.17–1.65) | 0.27(0.17–0.44) | 1.82(0.74–3.91)a | 0.014 |
T, nmol/ | 2.36(1.66–2.75) | 2.36(1.4–2.83)b,d | 2.4(1.83–2.63)c,e | 1.63(1.39–1.87) | 1.6(1.4–1.79) | 1.73(1.02–2.03) | < 0.001 |
SHBG, nmol/L | 23.3(14.6–45.7) | 35.05(20.58–66.28) | 18.7(11.3–29.7)c,e,f | 41.75(30.73–60.05) | 50.2(38.7–62.75) | 32.85(18.58–39.6)a | < 0.001 |
FAI | 9.29(4.46–15.25) | 5.57(2.81–11.43)b | 12.54(7.27–19.73)c,e,f | 3.61(2.48–5.2) | 3.19(2.45–4.44) | 5.4(2.61–7.73)a | < 0.001 |
A2, μg/dL | 5.9(4.22–7.98) | 4.52(2.14–6.97) | 6.49(4.83–9.5)c,e | 2.85(2.24–5.52) | 2.97(2.26–5.64) | 2.73(2.11–5.83) | 0.019 |