Fig. 5
From: Uterine Foxl2 regulates the adherence of the Trophectoderm cells to the endometrial epithelium
Foxl2 effect on the expression of Wnt/Fzd family members. a, d, g The expression of Fzd6 and Wnt11 is higher, while the expression of Kremen2, a Wnt/Fzd family inhibitor, is lower in receptive endometrial Ishikawa cells, which express low Foxl2 levels, compared to AN3-CA endometrial non-receptive cells, which express higher levels of Foxl2. b, e, h Knockdown of Foxl2 in AN3-CA leads to an increase in Fzd6 and Wnt11 expression and a reduction in Kremen2 levels. c, f, i Overexpression of Foxl2 in Ishikawa cells leads to a decrease in Fzd6 and Wnt11 levels but elevates Kremen2 levels. * p < 0.05