Fig. 1

Receiver operating characteristic (ROC) curves for ongoing pregnancy and miscarriage. a Analysis for binary classification euploid (< 20% aneuploid cells) vs. mosaic embryos (20% to 80% aneuploid cells) based on trophectoderm sample. b Various thresholds of aneuploidy within the cohort of mosaic embryos ranging from 20% to 80% in 10% increments. Predictor variable: proportion of abnormal cells in a trophectoderm biopsy specimen. Outcomes: ongoing pregnancy and miscarriage. Area under the curve (AUC) of 0.50 denotes the screening test as having no predictive ability while an AUC of 1.0 denotes an ideal screening test