Fig. 2
Respiration and oxidant emission from mitochondria isolated from the liver and skeletal muscle of age-matched rats that did not reproduce (NR), and rats that did not (PP) or did (PL) suckle their young for 21 days postpartum. Data include liver (a) state 3 respiration utilizing complex I substrates (pyruvate and malate; P/M), (b) state 4 respiration utilizing P/M, (c) respiratory control ratio (RCR) utilizing P/M), (d) state 3 respiration utilizing complex II substrates (succinate; suc), (e) state 4 respiration utilizing Suc, f RCR utilizing suc. Data also include skeletal muscle (g) state 3 respiration utilizing P/M, (h) state 4 respiration utilizing P/M, (i) RCR utilizing P/M, (j) state 3 respiration utilizing suc, (k) state 4 respiration utilizing suc, (l) RCR utilizing suc. Finally (m) oxidant emission from liver and (n) oxidant emission from skeletal muscle are also presented. Oxygen consumption and hydrogen peroxide (H2O2) rates were normalized to citrate synthase (CS). Data shown are mean ± SD. * indicates different from NR (p < 0.05), and # indicates different from PP (p < 0.05)