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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling

Fig. 3

Immunofluorescence analysis of follicular defects in TGFBR1-CAG9Cre mice. a-f Double immunofluorescence of DDX4 (red) and ACTA2 (green) using PD12 control (a-c) and TGFBR1-CAG9Cre (d-f) mice. Three independent samples per group were analyzed using immunohistochemistry and/or immunofluorescence. Note the presence of large follicles or abnormal follicle-like structures (dotted yellow lines) in the ovaries of TGFBR1-CAG9Cre mice in comparison with age-matched controls. Scale bar is representatively depicted in (a), and equals 100 μm (a-f)

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