Table 5 Gene with Differentiation Methylated Regions across puberty

Upregulation gene ID(Log2 Ratio)

299,907(20), 117,261(3.369), 302,424(2.585),315,059(2.563),361,576(2.478), 287,534(2.17),310,926(1.939),

24,896(1.893), 306,761(1.893),297,604(1.728), 24,944(1.585), 116,727(1.497),116,728(1.497), 29,714(1.447),

366,270(2.433),24,896(1.893),

29,589(1.441), 363,256(1.396), 24,413(1.379), 288,271(1.344),25,177(1.322),308,022(1.287),

29,361(1.485),288,271(1.344),

681,377(1.278),369,017(1.263), 280,670(1.239), 29,185(1.233), 246,299(1.182),

25,177(1.322),83,533(1.322),

498,194(1.162), 314,694(1.158), 362,945(1.138), 64,553(1.129), 300,653(1.115), 79,219(1.112), 303,678(1.105),

314,746(1.234), 299,266(1.155)

64,445(1.064), 313,022(1.059), 317,346(1.044), 29,616(1.034), 362,456(1.034), 84,573(1.033), 81,678(1.019), 301,056(1.016), 24,409(1), 85,251(1)

Downregulation gene ID(Log2 Ratio)

317,425(−2.17),501,559(−1.396)

94,268(−3.7), 293,976(−2.28), 313,596(−1.632), 361,833(−1.423), 287,709(−1.415), 501,559(−1.396), 360,973(−1.363), 297,096(−1.268), 306,141(306141), 308,099(−1.23)