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Table 6 Morphokinetic characteristics of human cryopreserved embryos after thawing/warming in dataset 2. P-values are based on a clustered logrank test. Hazard ratios and 95% CIs are based on simple random effects Cox proportional hazards regression models, modeling mother as random effect

From: Effect of day 3 embryo morphometrics and morphokinetics on survival and implantation after slow freezing-thawing and after vitrification-warming: a retrospective cohort study

  N cells at freezing
mean±SD
Mitosis resumption
N (%)
Hours to mitosis resumption
Median
HR 95% CI P Compaction
N (%)
Hours to Compaction
Median
HR 95% CI P
All embryos 8.1±1.5 67 (74) 9.9     42 (47) NA    
Type of freezing
 Slow freezing 8.0±1.6 22 (63) 13.1 0.49 0.27 to 0.88 0.0185 8 (23) NA 0.22 0.10 to 0.51 0.0001
 Vitrification 8.1±1.5 45 (82) 7.6 34 (62) 18.1
Intact
 No 8.1±1.7 21 (66) 14.6 1.86 1.04 to 3.31 0.0335 11 (34) NA 2.28 1.03 to 5.05 0.0638
 Yes 8.1±1.4 46 (79) 7.6 31 (53) 20.1
Implanted
 No 8.2±1.7 47 (69) 11.5 nc nc 0.2062 27 (40) NA nc nc 0.1345
 Yes 7.6±0.6 13 (93) 7.2 9 (64) 17.6
  1. Nc not computed because the model did not converge
  2. NA median time cannot be computed as less than half of the embryos reached the outcome