Effect of day 3 embryo morphometrics and morphokinetics on survival and implantation after slow freezing-thawing and after vitrification-warming: a retrospective cohort study

Table 5 Morphometric parameters after thawing/warming for implanted and not implanted embryos in dataset 1. Differences between implanted and not implanted embryos were calculated for each parameter using linear regression (95% CI and p values)

Freezing method	Parameter	Implanted Mean ± SD	Not implanted Mean ± SD	Coefficient implanted vs not implanted	95% CI	P
	n	6	42
Slow freezing	TCV, μm ³	666,658 ± 167,567	531,951 ± 143,637	134,721	−1689 to 271,131	0.0526
	N blastomeres	9.0 ± 2.5	6.8 ± 2.4	2.2	−0.1 to 4.5	0.0557
	% Symmetry	75.0 ± 7.2	77.1 ± 9.2	−1.9	−10.3 to 6.6	0.6465
	n	9	53^a
Vitrification	TCV, μm ³	729,666 ± 102,954	693,512 ± 137,507	24,599	−76,439 to 125,638	0.6219
	N blastomeres	9.4 ± 2.8	8.2 ± 2.4	1.2	−0.6 to 3.1	0.1883
	% Symmetry	67.4 ± 9.3	71.5 ± 9.6	−4.0	−10.9 to 2.8	0.2364

Random intercept correction was used to account for clustering
Bonferroni-Holm method was used per freezing method to correct for multiple testing
No morphometrics could be analyzed in compacted embryos
^a3 embryos were compacted after thawing

ISSN: 1477-7827