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Table 2 Morphometric parameters during fresh culture before slow freezing or vitrification for survived and not survived embryos in dataset 1. Differences between survived and not survived embryos were calculated for each parameter using linear regression (95% CI and p values)

From: Effect of day 3 embryo morphometrics and morphokinetics on survival and implantation after slow freezing-thawing and after vitrification-warming: a retrospective cohort study

Freezing method Parameter Survived
Mean ± SD
Not survived
Mean ± SD
Coefficient
survived vs
not survived
95% CI P
Slow freezing n 71b 66c    
TCV, μm 3 715,113 ± 86,190 719,250 ± 98,140 −1309 −30,401 to 27,783 0.9289
N blastomeres 8.2 ± 1.9 8.1 ± 1.3 0.02 −0.55 to 0.59 0.9371
% Fragmentation a 13.7 ± 10.2 15.0 ± 9.6 −0.88 −4.25 to 2.49 0.6040
% Symmetry 73.5 ± 8.2 71.1 ± 9.2 2.32 −0.63 to 5.28 0.1218
Vitrification n 104d 14    
TCV, μm 3 727,513 ± 101,655 688,627 ± 112,499 60,008 7159 to 112,858 0.0267
N blastomeres 8.2 ± 1.8 8.9 ± 2.4 −0.19 −1.24 to 0.86 0.7164
% Fragmentation 14.0 ± 10.0 19.3 ± 10.8 −5.55 −11.3 to 0.20 0.0584
% Symmetry 72.4 ± 8.6 76.8 ± 6.8 −4.93 −9.72 to −0.15 0.0435
  1. Random intercept correction was used to account for clustering
  2. Bonferroni-Holm method was used per freezing method to correct for multiple testing
  3. a1 embryo excluded because ≤ − 20% fragmentation
  4. No morphometrics could be analyzed in compacted embryos
  5. b8/79 embryos were compacted at evaluation
  6. c6/72 embryos were compacted at evaluation
  7. d8/112 embryos were compacted at evaluation