Fig. 5From: In vitro progesterone production by luteinized human mural granulosa cells is modulated by activation of AMPK and cause of infertilityProgesterone production by granulosa cells in non-pregnant versus pregnant patients. Progesterone production in mural granulosal cells was affected by pregnancy status post in-vitro fertilization (IVF). Luteinized mural granulosa cells from patients who became pregnant to the IVF cycle produced significantly more progesterone when stimulated with hCG than those who did not become pregnant (2.4 vs. 1.8 ng/ml; P < 0.05). Asterisks indicate a difference of (P < 0.05) from control value with pregnancy outcome. Cells were treated with PGF2α (0.1 μg/ml) or hCG (5 IU/ml). N values for each treatment group are given in parenthesis above each columnBack to article page