Fig. 4From: In vitro progesterone production by luteinized human mural granulosa cells is modulated by activation of AMPK and cause of infertilityProgesterone production by granulosa cells from patients with different body mass indexes. Patients with normal body mass index [BMI] (18.5–24.9) had a significant increase in progesterone production when treated with hCG (P < 0.0001). Cells of patients who were categorized as overweight (BMI 25–29.9) or obese (BMI >30) did not have an increase in progesterone production when stimulated with hCG (P > 0.05). Asterisks indicate a difference of (P < 0.05) from control value with BMI categories. Cells were treated with PGF2α (0.1 μg/ml) or hCG (5 IU/ml). N values for each treatment group are given in parenthesis above each columnBack to article page