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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: The regulation of ovary and conceptus on the uterine natural killer cells during early pregnancy

Fig. 2

KIR-A/homologous C2 and KIR-B/homologous C1 are two high-risk combination. a All possible combination of maternal KIR haplotypes with trophoblastic HLA-C ligands. Combinations with intensive inhibition are failure to activate uNK cells to secrete relevant angiogenic cytokines and more vulnerable to undergo pregnancy losses. Thus, KIR-A/homologous C2 and KIR-B/homologous C1 are two high-risk combinations than other combinations. b Binding properties of the main KIRs for fetal HLA-C

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