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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Plk1 is essential for proper chromosome segregation during meiosis I/meiosis II transition in pig oocytes

Fig. 3

Effect of GSK461364 treatment during MI-to-MII stage on pbI extrusion of porcine oocytes. (a) Most of the control oocytes extruded pbI and finished meiotic maturation while a significantly larger proportion of the GSK461364 treated oocytes failed to extrude pbI. Scale bar, 20 μm. (b) The rate of extruding pbI was decreased in a dose-dependent manner in GSK461364-treated groups. (c) GSK461364 treatment significantly eliminated the phosphorylation of Plk1 in porcine oocytes. ** P < 0.01; *** P < 0.001

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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