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Table 4 Comparison of upstream regulator by IFNT treatment in bovine young and aged endometrial cells

From: Age-associated mRNA expression changes in bovine endometrial cells in vitro

Young

Upstream regulator

p-value

Activation z-score

Prediction activation state

Aged

Upstream regulator

p-value

Activation z-score

Prediction activation state

1

IRF7

2.44E-48

5.350

Activated by IFNT

1

IRF7

8.25E-54

5.603

Activated by IFNT

2

EIF2AK2

1.40E-19

2.893

Activated by IFNT

2

EIF2AK2

2.09E-17

3.426

Activated by IFNT

3

DDX58

2.82E-20

2.635

Activated by IFNT

3

DDX58

4.47E-22

2.818

Activated by IFNT

Young

Upstream regulator

p-value

Activation z-score

Prediction activation state

Aged

Upstream regulator

p-value

Activation z-score

Prediction activation state

1

USP18

2.82E-14

−2.592

Inhibited by Aged

1

USP18

1.51E-09

−2.213

Inhibited by Aged