Table 3 Comparison of canonical pathways by IFNT treatment in bovine young and aged endometrial cells
From: Age-associated mRNA expression changes in bovine endometrial cells in vitro
Young | Name of canonical pathways | zScore | p-value | Molecules |
1 | Interferon Signaling | 2.65 | 1.58E-13 | IFITM3, IFIT1, IFIT3, MX1, IRF9, IFI6, IFITM2, ISG15 |
2 | Retinoic acid Mediated Apoptosis Signaling | 2.24 | 1.29E-06 | PARP10, TNFSF10, PARP12, PARP9, PARP14 |
3 | Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses | 2.00 | 2.45E-06 | IFIH1, IL-1A, IRF7, OAS2, DDX58, EIF2AK2 |
4 | Death Receptor Signaling | 2.24 | 9.77E-06 | PARP10, TNFSF10, PARP12, PARP9, PARP14 |
5 | UVA-induced MAPK signaling | 2.00 | 1.62E-04 | PARP10, PARP12, PARP9, PARP14 |
Aged | Name of canonical pathways | zScore | p-value | Molecules |
1 | Interferon Signaling | 2.45 | 1.66E-09 | IFIT1, IFIT3, MX1, IFI6, IFITM2, ISG15 |
2 | Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses | 2.00 | 5.37E-05 | IFIH1, IRF7, OAS2, DDX58, EIF2AK2 |
3 | Retinoic acid Mediated Apoptosis Signaling | 2.00 | 5.50E-05 | PARP10, PARP12, PARP9, PARP14 |
4 | UVA-induced MAPK signaling | 2.00 | 1.99E-04 | PARP10, PARP12, PARP9, PARP14 |
5 | Death Receptor Signaling | 2.00 | 2.24E-04 | PARP10, PARP12, PARP9, PARP14 |